Evidence map›Paper›PMID 39470193›Full record

ArticlemBio2024

Activation of the general stress response sigma factor SigB prevents competence development in

Marco Harms, Stephan Michalik, Petra Hildebrandt, Marc Schaffer, Manuela Gesell Salazar, Ulf Gerth, Ulrike Mäder, Jan Maarten van Dijl, Michael Hecker, Uwe Völker and 1 more

Abstract read
In one paragraph

Article in mBio, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Gene expression dynamics inFrontiers in microbiology · 2025
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Marco HarmsUniversity Medicine Greifswald, Center for Functional Genomics of Microbes, Interfaculty Institute for Genetics and Functional Genomics, Greifswald, Germany.
Stephan MichalikUniversity Medicine Greifswald, Center for Functional Genomics of Microbes, Interfaculty Institute for Genetics and Functional Genomics, Greifswald, Germany.ORCID 0000-0002-6550-0132
Petra HildebrandtUniversity Medicine Greifswald, Center for Functional Genomics of Microbes, Interfaculty Institute for Genetics and Functional Genomics, Greifswald, Germany.
Marc SchafferUniversity Medicine Greifswald, Center for Functional Genomics of Microbes, Interfaculty Institute for Genetics and Functional Genomics, Greifswald, Germany.
Manuela Gesell SalazarUniversity Medicine Greifswald, Center for Functional Genomics of Microbes, Interfaculty Institute for Genetics and Functional Genomics, Greifswald, Germany.
Ulf GerthUniversity of Greifswald, Center for Functional Genomics of Microbes, Institute of Microbiology, Greifswald, Germany.
Ulrike MäderUniversity Medicine Greifswald, Center for Functional Genomics of Microbes, Interfaculty Institute for Genetics and Functional Genomics, Greifswald, Germany.ORCID 0000-0003-2873-0999
Jan Maarten van DijlDepartment of Medical Microbiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.ORCID 0000-0002-5688-8438
Michael HeckerUniversity Medicine Greifswald, Center for Functional Genomics of Microbes, Interfaculty Institute for Genetics and Functional Genomics, Greifswald, Germany.
Uwe VölkerUniversity Medicine Greifswald, Center for Functional Genomics of Microbes, Interfaculty Institute for Genetics and Functional Genomics, Greifswald, Germany.ORCID 0000-0002-5689-3448
Alexander RederUniversity Medicine Greifswald, Center for Functional Genomics of Microbes, Interfaculty Institute for Genetics and Functional Genomics, Greifswald, Germany.ORCID 0009-0005-3575-6849

Funding

Universität Greifswald (University of Greifswald) Scholarship
6 · The paper itself

Abstract

Seemingly simple bacteria mount intricate adaptive responses when exposed to physical stress or nutrient limitation, and the activation of these responses is governed by complex signal transduction networks. Upon entry into the stationary growth phase, the soil bacterium IMPORTANCE:

Indexed as

Bacillus subtilisBacterial ProteinsGene Expression Regulation, BacterialSigma FactorStress, PhysiologicalDNA Transformation CompetenceLightTranscription FactorsBacterial ProteinscomK protein, Bacillus subtilisSigB protein, BacteriaSigma FactorTranscription Factorsas-comK (feature S365)ComKComK anti-sense RNAcompetence developmentgeneral stress responseSigBSpo0Asporulation

Identifiers

PMID39470193
PMCPMC11633097

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.