Evidence map›Paper›PMID 39470056›Full record

ArticleTechnology in cancer research & treatment

Physical and Dosimetric Characterization of Silicone Rubber Bolus for Head Photon-Beam Radiotherapy.

Xuemei Chen, Wei Wang, Xiaotong Huang, Wenchao Diao, Chendi Xu, Lecheng Jia, Hua Li, Bin Li, Xiaobo Jiang

Abstract read
In one paragraph

Article in Technology in cancer research & treatment. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xuemei ChenState Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, P. R. China.ORCID 0000-0003-1909-8530
Wei WangState Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, P. R. China.
Xiaotong HuangState Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, P. R. China.
Wenchao DiaoState Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, P. R. China.
Chendi XuState Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, P. R. China.
Lecheng JiaShenzhen United Imaging Research Institute of Innovative Medical Equipment, Shenzhen, Guangdong Province, China.
Hua LiShenzhen United Imaging Research Institute of Innovative Medical Equipment, Shenzhen, Guangdong Province, China.
Bin LiState Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, P. R. China.ORCID 0000-0002-2413-5175
Xiaobo JiangState Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, P. R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study assesses the physical properties of the silicone rubber (SR) bolus, compares its dosimetric characterization with those of gel and thermoset boluses, aiming to evaluate the feasibility and stability of utilizing SR bolus for head photon-beam radiotherapy.

methodsThree types of boluses (gel, thermoset, and SR) were prepared with same dimensions. Firstly, the physical properties of SR bolus (density, tensile strength and hardness) were assessed pre-irradiation and post-irradiation. Secondly, the percentage of depth dose (PDD) curve was calculated using the treatment planning system (TPS) and measured with a plane-parallel. Thirdly, these three boluses were individually placed on the head phantom, followed by computed tomography (CT) scans to delineate the customized target area and organs at risk (OARs) for treatment planning. Over the subsequent three weeks, fan-beam CT (FBCT) images were obtained weekly and registered with the initial CT to modify the target area and OARs. Fourthly, the adhesion differences, dose distributions, and inter-fraction reproducibility of the three boluses were compared and evaluated.

resultsThe results observed that post-irradiated SR bolus exhibited higher hardness values (

conclusionThe SR bolus can be fabricated at room temperature, adheres to irregular body surfaces, and retains its physical properties post-irradiation. Additionally, this bolus has comparable dosimetric characterization to other commercial boluses, and may provide notable protection for OARs. Therefore, the SR bolus is recommended as a feasible and stable material for head photon-beam radiotherapy.

Indexed as

Phantoms, ImagingRadiotherapy DosageRadiotherapy Planning, Computer-AssistedSilicone ElastomersHeadHumansOrgans at RiskPhotonsRadiometryTomography, X-Ray ComputedSilicone Elastomersair gapbolusdosimetryphoton-beam radiotherapysilicone rubber

Identifiers

PMID39470056
PMCPMC11528799

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.