Evidence map›Paper›PMID 39469969›Full record

ReviewJournal of cosmetic dermatology2025

Effects of Thioglycolate Compounds in an Emerging Technique in the World of Cosmetics-Brow Lamination.

Laura Ghanem, Stephani Chagoury, Andrea Issa, Kaline Maya Khoury, Kelly Katherine Karam, Milissa Makhlouf

Abstract readReview
In one paragraph

Review in Journal of cosmetic dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Laura GhanemFaculty of Medical Sciences, Lebanese University, Beirut, Lebanon.ORCID https://orcid.org/0009-0009-7918-0107
Stephani ChagouryFaculty of Medicine, University of Balamand, Tripoli, Lebanon.ORCID https://orcid.org/0009-0008-4057-9535
Andrea IssaFaculty of Medicine, University of Balamand, Tripoli, Lebanon.ORCID https://orcid.org/0009-0000-7015-8709
Kaline Maya KhouryFaculty of Medicine, University of Balamand, Tripoli, Lebanon.ORCID https://orcid.org/0009-0008-6616-2324
Kelly Katherine KaramFaculty of Medicine, University of Balamand, Tripoli, Lebanon.ORCID https://orcid.org/0009-0002-6998-6288
Milissa MakhloufFaculty of Medicine, University of Balamand, Tripoli, Lebanon.ORCID https://orcid.org/0000-0002-0137-7606

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe side effects of two related chemicals, ammonium thioglycolate (ATG) and thioglycolic acid (TGA) have been widely highlighted in the world of cosmetics. These thioglycolate compounds are considered essential ingredients in a new technique known as brow lamination. This technique is widely used nowadays, with the aim of changing the eyebrow shape.

aimsTo our knowledge, this is the first study to address the possible side effects of brow lamination.

resultsThe hydrophilic characteristic of ATG and TGA reflects their transdermal absorption through the intracellular and transappendageal pathways. These compounds can affect the skin through allergic contact dermatitis (ACD), characterized by skin irritation, dryness, and erythema. Moreover, these thioglycolates can alter several mechanical and chemical reactions in the eyebrows' hair, therefore affecting their shape, structure, and pigmentation. In addition, these chemicals contained in brow lamination can exert systemic manifestations, at the level of the reproductive, ocular, respiratory, and endocrine systems.

conclusionMore studies should be elaborated to shed light on the possible side effects of this trend. Additionally, further regulations should be taken into consideration to ensure the concentration and the measures applied are convenient to minimize these side effects.

Indexed as

CosmeticsCosmetic TechniquesThioglycolatesDermatitis, Allergic ContactHumans2-mercaptoacetateCosmeticsThioglycolatesammonium thioglycolatebrow laminationchemicalseyebrowsskin irritationthioglycolic acid

Identifiers

PMID39469969
PMCPMC11743338

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.