Evidence map›Paper›PMID 39469841›Full record

ArticleBiomarkers in medicine2024

WTAP-mediated m6A modification regulates NLRP3/Caspase-1/GSDMD to inhibit pyroptosis and exacerbate colorectal cancer.

Anwei Mo, Huaiwen Wang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomarkers in medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Review
  3. mRedox biology · 2026
    Review
  4. Review
  5. Article
  6. Caspase-1 in cancer and inflammatory diseases: a potential therapeutic target.Apoptosis : an international journal on programmed cell death · 2026
    Review
  7. Autophagy regulation of pyroptosis and ferroptosis: a new strategy for colorectal cancer treatment.Apoptosis : an international journal on programmed cell death · 2026
    Review
  8. Review
  9. Targeting RNA adenosine editing and modification enzymes for RNA therapeutics.Molecular therapy : the journal of the American Society of Gene Therapy · 2025
    Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Anwei MoDepartment of Oncology, Hainan General Hospital (Hainan Affiliated Hospital of Hainan Medical University), Haikou City, Hainan, 570311, China.
Huaiwen WangDepartment of Anorectal Surgery, Hainan General Hospital (Hainan Affiliated Hospital of Hainan Medical University), Haikou City, Hainan, 570311, China.ORCID 0009-0006-1371-3271

Funding

Project supported by the Education Department of Hainan Province Hnky2023-34Research Project of Health Industry in Hainan Province NO. 22A200193the Construction Project of Hainan Provincial Clinical Medical Center
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Caspase 1Colorectal NeoplasmsNLR Family, Pyrin Domain-Containing 3 ProteinPyroptosisAdenosineApoptosisCell Cycle ProteinsCell Line, TumorCell MovementCell ProliferationGasderminsHumansInflammasomesIntracellular Signaling Peptides and ProteinsPhosphate-Binding ProteinsRNA Splicing FactorsAdenosineCaspase 1Cell Cycle ProteinsGasderminsGSDMD protein, humanInflammasomesIntracellular Signaling Peptides and ProteinsNLR Family, Pyrin Domain-Containing 3 ProteinNLRP3 protein, humanN-methyladenosinePhosphate-Binding ProteinsRNA Splicing FactorsWTAP protein, humancolorectal cancerN6-methyladenosineNLRP3pyroptosisWilms' tumor 1-associating protein

Identifiers

PMID39469841
PMCPMC11633406

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.