Evidence map›Paper›PMID 39469761›Full record

SynthesisJournal of child and adolescent psychopharmacology2025

Deprescribing Antidepressants in Children and Adolescents: A Systematic Review of Discontinuation Approaches, Cross-Titration, and Withdrawal Symptoms.

Julia N Stimpfl, John T Walkup, Adelaide S Robb, Alexandra E Alford, Stephen M Stahl, James T McCracken, Stephani L Stancil, Laura B Ramsey, Graham J Emslie, Jeffrey R Strawn

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Journal of child and adolescent psychopharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Julia N StimpflDepartment of Psychiatry & Behavioral Neuroscience, College of Medicine, University of Cincinnati, Cincinnati, Ohio, USA.ORCID 0009-0005-6395-9010
John T WalkupPritzker Department of Psychiatry and Behavioral Health, Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois, USA.
Adelaide S RobbDepartment of Psychiatry and Behavioral Sciences, Children's National Hospital, George Washington University School of Medicine, Washington DC, USA.
Alexandra E AlfordDepartment of Psychiatry & Behavioral Neuroscience, College of Medicine, University of Cincinnati, Cincinnati, Ohio, USA.
Stephen M StahlDepartment of Psychiatry, University of California, San Diego, California, USA.
James T McCrackenDepartment of Psychiatry, University of California, San Francisco, California, USA.
Stephani L StancilDepartment of Pediatrics, Schools of Medicine, University of Missouri-Kansas City, Kansas City, Missouri, USA.ORCID 0000-0001-7308-3132
Laura B RamseyDepartment of Psychiatry & Behavioral Neuroscience, College of Medicine, University of Cincinnati, Cincinnati, Ohio, USA.ORCID 0000-0001-6417-3961
Graham J EmslieDepartment of Psychiatry, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Jeffrey R StrawnDepartment of Psychiatry & Behavioral Neuroscience, College of Medicine, University of Cincinnati, Cincinnati, Ohio, USA.ORCID 0000-0002-7526-2641

Funding

Development of a Pharmacodynamic Biomarker of Opioid Antagonism in Adolescents with Eating DisordersK23MH130728 · NIMH · CHILDREN'S MERCY HOSP (KANSAS CITY, MO) · PI Stephani L Stancil · 2023 to 2026
$740k
NIMH NIH HHS K23 MH130728
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antidepressive AgentsDeprescriptionsSubstance Withdrawal SyndromeAdolescentChildHumansRandomized Controlled Trials as TopicSelective Serotonin Reuptake InhibitorsSerotonin and Noradrenaline Reuptake InhibitorsAntidepressive AgentsSelective Serotonin Reuptake InhibitorsSerotonin and Noradrenaline Reuptake Inhibitorsantidepressantanxietydepressionselective serotonin reuptake inhibitor (SSRI)serotonin-norepinephrine reuptake inhibitor (SNRI)

Identifiers

PMID39469761
PMCPMC11971562

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.