Evidence map›Paper›PMID 39469696›Full record

ArticleHeliyon2024

Interfacial insights: [6]-Gingerol monolayers at the air-water interface and beyond.

Lara Adwan, Laura Dotor, María Graciela Pino, Adriana Gil, Santiago Martin, Pilar Cea

Abstract read
In one paragraph

Article in Heliyon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lara AdwanDepartamento de Química Física, Facultad de Ciencias, Universidad de Zaragoza, 50009, Zaragoza, Spain.
Laura DotorDepartamento de Química Física, Facultad de Ciencias, Universidad de Zaragoza, 50009, Zaragoza, Spain.
María Graciela PinoDepartamento de Química Física, Facultad de Ciencias, Universidad de Zaragoza, 50009, Zaragoza, Spain.
Adriana GilDepartamento de Química Física, Facultad de Ciencias, Universidad de Zaragoza, 50009, Zaragoza, Spain.
Santiago MartinDepartamento de Química Física, Facultad de Ciencias, Universidad de Zaragoza, 50009, Zaragoza, Spain.
Pilar CeaDepartamento de Química Física, Facultad de Ciencias, Universidad de Zaragoza, 50009, Zaragoza, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ginger is a culinary spice with a millennia-old tradition due to its extensive therapeutic applications, recently validated by scientific studies. In particular [6]-Gingerol, a key active molecule in ginger, exhibits extraordinary capabilities in addressing a wide spectrum of health issues. However, its therapeutic potential is limited by its rather low bioavailability. The incorporation of [6]-Gingerol into membrane systems of liposomes, micelles, or exosomes is a promising strategy to overcome this limitation. In this contribution, we report the hitherto unexplored surface properties of [6]-Gingerol at the air-water interface. Our comprehensive study, which includes a detailed analysis of surface pressure and surface potential vs. area per molecule isotherms, surface compression modulus, and Brewster Angle Microscopy, demonstrates the capability of [6]-Gingerol to form Langmuir films. These films can be transferred onto solid substrates, forming remarkably homogeneous Langmuir-Blodgett films which have been characterized by Quartz Crystal Microbalance and Atomic Force Microscopy. This study may be of interest as it paves the way for future research on introducing [6]-Gingerol into membrane systems and transporting it into living cells.

Indexed as

[6]-GingerolLangmuir-Blodgett filmsLangmuir filmsSurface behavior

Identifiers

PMID39469696
PMCPMC11513447

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.