Evidence map›Paper›PMID 39469596›Full record

ArticleRadiology case reports2025

Teratogenic effect of Misoprostol following failure of elective abortion: A case of femoral agenesis and review of the literature.

Hiba Ben Abdelhafidh, Oumayma Ben Rejeb, Nour Rouis, Badra Bannour, Neila Fathallah, Imen Bannour

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Radiology case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hiba Ben AbdelhafidhUniversity of Sousse, Faculty of Medicine of Sousse, Obstetrics and Gynecology Department, University Hospital Farhat Hached of Sousse, Tunisia.
Oumayma Ben RejebUniversity of Sousse, Faculty of Medicine of Sousse, Obstetrics and Gynecology Department, University Hospital Farhat Hached of Sousse, Tunisia.
Nour RouisUniversity of Sousse, Faculty of Medicine of Sousse, Obstetrics and Gynecology Department, University Hospital Farhat Hached of Sousse, Tunisia.
Badra BannourUniversity of Sousse, Faculty of Medicine of Sousse, Obstetrics and Gynecology Department, University Hospital Farhat Hached of Sousse, Tunisia.
Neila FathallahUniversity of Sousse, Department of Pharmacology, Faculty of Medicine of Sousse, Tunisia.
Imen BannourUniversity of Sousse, Faculty of Medicine of Sousse, Obstetrics and Gynecology Department, University Hospital Farhat Hached of Sousse, Tunisia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Misoprostol, a synthetic analogue of prostaglandin E1, is commonly used in gynecology, particularly in combination with mifepristone for elective abortion. Although its use is widespread, the potential teratogenic effects of misoprostol in cases of failed medical abortion have not been sufficiently explored in the medical literature. Severe congenital malformations, although rare, have been reported, raising concerns about the impact of this drug on fetal development. We present a rare case of femoral agenesis observed in a woman who experienced a failed medical abortion with Misoprostol (Cytotec®), highlighting the need for a better understanding of the risks associated with fetal exposure to this drug and the implementation of rigorous follow-up measures after its use.

Indexed as

Femoral agenesisFollow-up ultrasoundMisoprostolTeratogenicity

Identifiers

PMID39469596
PMCPMC11513674

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.