Evidence map›Paper›PMID 39469584›Full record

ArticleClinicoEconomics and outcomes research : CEOR2024

Economic Impact of Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) in Italy. Analysis and Perspectives.

Enrico Torre, Sergio Di Matteo, Chiara Martinotti, Giacomo Matteo Bruno, Umberto Goglia, Gianni Testino, Alberto Rebora, Luigi Carlo Bottaro, Giorgio Lorenzo Colombo

Abstract read
In one paragraph

Article in ClinicoEconomics and outcomes research : CEOR, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
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  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Enrico TorreDiabetology and Metabolic Diseases Unit - ASL3, Genoa, Italy.ORCID 0000-0002-4375-7383
Sergio Di MatteoCenter of Research, SAVE Studi - Health Economics and Outcomes Research, Milan, Italy.
Chiara MartinottiCenter of Research, SAVE Studi - Health Economics and Outcomes Research, Milan, Italy.ORCID 0000-0001-6304-9977
Giacomo Matteo BrunoDepartment of Drug Sciences, University of Pavia, Pavia, Italy.ORCID 0000-0003-4571-654X
Umberto GogliaTerritorial Diabetology Unit, ASLCN1, Cuneo, Italy.
Gianni TestinoUnits of Addiction and Hepatology, ASL3, Genoa, Italy.
Alberto ReboraDiabetology and Metabolic Diseases Unit - ASL3, Genoa, Italy.
Luigi Carlo BottaroGeneral Direction, ASL3, Genoa, Italy.
Giorgio Lorenzo ColomboDepartment of Drug Sciences, University of Pavia, Pavia, Italy.ORCID 0000-0002-5790-8891

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Metabolic dysfunction-associated steatotic liver disease (MASLD) is a multisystem condition destined to become pandemic in the coming decades. This study aimed at evaluating the economic impact of MASLD in the Italian population from the Italian National Healthcare Service (NHS) perspective. Methods: The economic impact of the MASLD was assessed by developing a calculation model in Microsoft Excel Results: Based on an estimated 11,546,370 MASLD target population, an annual illness impact of €12,251,631,822 was calculated, corresponding to a difference of €7,731,674,054 compared with the same sample size without MASLD. Moreover, the MASLD population is expected to experience 13,438 additional deaths annually. Conclusion: The growing epidemiological impact of MASLD and its complications represent a huge economic burden for healthcare services worldwide. An integrated approach, including changes in lifestyle behaviors, will be the first step. Specific drugs for MASLD are not yet available; however, studies are underway, and combined pharmaceutical therapies may be an inevitable choice to achieve adequate control of MASLD and its complications.

Indexed as

complicationshealthcare costsMASLD burden in Italymetabolic associated fatty liver disease MASLDtreatment and perspectives

Identifiers

PMID39469584
PMCPMC11514691

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.