Evidence map›Paper›PMID 39469466›Full record

ReviewVascular health and risk management2024

Primary CNS Vasculitis - A Focussed Review on Treatment.

Praveen Kesav, Divya Manesh Raj, Rula A Hajj-Ali, Syed I Hussain, Seby John

Abstract readReview
In one paragraph

Review in Vascular health and risk management, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Tumor-mimicking primary CNS vasculitis: illustrative case.Journal of neurosurgery. Case lessons · 2026
    Article
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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Praveen KesavDepartment of Neurology, Neurological Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates.ORCID 0000-0003-2737-9770
Divya Manesh RajResearch Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates.
Rula A Hajj-AliDepartment of Rheumatic and Immunologic Diseases, Center for Vasculitis Care and Research, Cleveland Clinic Lerner College of Medicine, Cleveland, OH, USA.
Syed I HussainDepartment of Neuro-Interventional Surgery, Neurological Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates.ORCID 0000-0002-5086-8030
Seby JohnDepartment of Neuro-Interventional Surgery, Neurological Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates.ORCID 0000-0003-0894-0657

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary central nervous system vasculitis (PCNSV) is a rare and complex disease that poses formidable diagnostic and therapeutic challenges. Since its initial recognition as a distinct clinical entity in the 1950s, there has been considerable advancement in our understanding of PCNSV histopathology, specific clinical subsets, and their response to treatment. However, PCNSV is one of the rarest vasculitides, and still remains a challenging diagnosis with many unanswered questions regarding optimal management. In this review, we intend to provide a detailed outline of approaches that are currently being employed for the treatment of PCNSV. We exhaustively review available cohort series of PCNSV and critically appraise the data for study definitions, treatment approaches, and predictors of treatment outcomes. Finally, we also propose a treatment approach for PCNSV.

Indexed as

Vasculitis, Central Nervous SystemAdultFemaleHumansImmunosuppressive AgentsMaleRisk FactorsTreatment OutcomeImmunosuppressive AgentsinductionmaintenanceoutcomesPACNSPCNSVprimary angiitis of CNSprimary CNS vasculitisrelapseremissiontreatment

Identifiers

PMID39469466
PMCPMC11514685

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.