ArticleIndian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion2024
A Comparative Analysis of Freelite and N Latex FLC Assay for the sFLC Measurements in Suspected Patients of Monoclonal Gammopathy.
Article in Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Serum free light chain concentration and ratio-based criterion for myeloma-defining event, in its current version, is untenable.British journal of haematology · 2026Review
- Clinical significance of FLC tests in patients without other evidence of hematologic disorder.Clinical and experimental medicine · 2024Article
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8 authors.
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Abstract
With the introduction of newer platforms for sFLC estimation, more comparative attempts are required to establish an assay-specific reference range, that can be used in the day-to-day clinical management of the patients, as the revised criteria for the diagnosis of myeloma recommend the use of involved Free light chain (FLC)/uninvolved FLC ratio as myeloma defining event, solely relying on Freelite assay. This was an observational study that included 101 patients, 55 (54.5%) with M-protein (myeloma), and 46 (45.5%) without M-protein. The estimation of the sFLC assay was carried out at two separate platforms, the Freelite Assay (The binding Site, Birmingham, UK) on a Siemens BNII Nephelometer, and the N Latex FLC reagent on Atellica NEPH 630 (Siemens Healthineers, Eschborn, Germany). The comparative correlational analysis of the two assays for estimation of κ-,
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