Evidence map›Paper›PMID 39469123›Full record

ArticleFrontiers in cardiovascular medicine2024

Association between ablation-induced baroreceptor reflex modification and procedure efficacy in patients with atrial fibrillation.

Anna Zuk, Roman Piotrowski, Agnieszka Sikorska, Ilona Kowalik, Piotr Kulakowski, Jakub Baran

Abstract read
In one paragraph

Article in Frontiers in cardiovascular medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Anna ZukDepartment of Cardiology, Centre of Postgraduate Medical Education, Grochowski Hospital, Warsaw, Poland.
Roman PiotrowskiDepartment of Cardiology, Centre of Postgraduate Medical Education, Grochowski Hospital, Warsaw, Poland.
Agnieszka SikorskaDepartment of Cardiology, Centre of Postgraduate Medical Education, Grochowski Hospital, Warsaw, Poland.
Ilona KowalikClinical Research Support Center, National Institute of Cardiology, Warsaw, Poland.
Piotr KulakowskiDepartment of Cardiology, Centre of Postgraduate Medical Education, Grochowski Hospital, Warsaw, Poland.
Jakub BaranDepartment of Cardiology, Centre of Postgraduate Medical Education, Grochowski Hospital, Warsaw, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The autonomic nervous system (ANS) plays a significant role in atrial fibrillation (AF). Catheter ablation (CA) is a well-established treatment method for AF and significantly affects the ANS, including baroreceptor (BR) function. However, little is known about the changes in BR function caused by radiofrequency (RF) or cryoballoon energy (CB) and its impact on future AF recurrences. Purpose: To assess 1-year efficacy of CA of AF in relation to BR function modification and type of ablation energy used. Methods: The study group consisted of 78 patients (25 females, mean age 58 ± 9 years) with paroxysmal AF and first CA (39 patients in the RF group and 39 in the CB group). The BR function was assessed non-invasively, using tilt testing before and after CA, and three BR parameters were calculated: event count (BREC) depicting overall BR activity, slope mean depicting BR sensitivity (BRS), and BR effectiveness index (BEI). The efficacy of CA was assessed during 1-year follow-up, which consisted of ambulatory visits and 24-h Holter ECG recordings at 3, 6, and 12 months after CA. The quality of life was assessed by using a dedicated scale [University of Toronto Atrial Fibrillation Severity Scale (AFSS)]. Results: The two groups did not show differences in terms of clinical or demographic data. One-year follow-up was completed for 35 (89.7%) patients from the CB group and for 34 (87.2%) from the RF group. The rates of efficacy of CB and RF were similar [31/35 (88.6%) vs. 26/34 (76.5%), respectively]. After CA, the BR function decreased in both groups, with a significantly greater decrease in the CB group. The changes in BR parameters were similar in both responders and non-responders after CA in the whole group [BREC 10.0 (2.0-24.0) vs. 12.0 (4.0-21.5), Conclusions: CA for AF significantly decreased the BR function, especially in patients undergoing CB. There was no correlation between CA-induced changes in BR parameters and ablation outcome.

Indexed as

ablation efficacyatrial fibrillationatrial fibrillation symptomsautonomic nervous systembaroreceptor reflex

Identifiers

PMID39469123
PMCPMC11513264

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