Evidence map›Paper›PMID 39468938›Full record

ArticleHistology and histopathology2025

STAT3/p-STAT3 expression is correlated with clinicopathological characteristics and prognosis in non-small cell lung cancer.

Jili Li, Yingying Zhu, Jianyue Peng, Lan Yang, Li Zhang, Lei Li

Abstract read
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In one paragraph

Article in Histology and histopathology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jili Li *West China School of Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan, PR China.
Yingying Zhu *Department of Respiratory and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan, PR China.
Jianyue PengWest China School of Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan, PR China.
Lan YangDepartment of Respiratory and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan, PR China.
Li ZhangDepartment of Respiratory and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan, PR China.
Lei LiDepartment of Respiratory and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan, PR China. lilei41lilei@163.com.

Funding

National Natural Science Foundation of China 32201231
6 · The paper itself

Abstract

Signal transducer and activator of transcription factor 3 (STAT3)/phosphorylated STAT3 (p-STAT) play a critical role in tumorigenesis, however, there is limited information on its prognostic value in non-small cell lung cancer (NSCLC). To address this question, 239 lung cancer and 71 normal lung tissue samples were obtained in this study. Immunohistochemistry was applied to detect STAT3/p-STAT3 expression. Pearson's Chi-squared test and the Kaplan-Meier method were conducted to evaluate associations with patients' clinical characteristics and survival. According to our results, STAT3/p-STAT3 was significantly upregulated in lung cancer tissue (

Indexed as

Biomarkers, TumorCarcinoma, Non-Small-Cell LungLung NeoplasmsSTAT3 Transcription FactorAdultAgedAged, 80 and overFemaleHumansImmunohistochemistryKaplan-Meier EstimateMaleMiddle AgedPhosphorylationPrognosisBiomarkers, TumorSTAT3 protein, humanSTAT3 Transcription Factor

Identifiers

PMID39468938

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.