Evidence map›Paper›PMID 39468628›Full record

ArticleCancer science2025

Evaluating stiffness of gastric wall using laser resonance frequency analysis for gastric cancer.

Tasuku Furube, Daisuke Nakashima, Satoru Matsuda, Katsuhiro Mikami, Takuto Hatakeyama, Masashi Takeuchi, Kazumasa Fukuda, Akihisa Ueno, Hajime Okita, Hirofumi Kawakubo and 3 more

Abstract read
In one paragraph

Article in Cancer science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Tasuku FurubeDepartment of Surgery, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan.
Daisuke NakashimaDepartment of Orthopaedic Surgery, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan.
Satoru MatsudaDepartment of Surgery, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan.ORCID https://orcid.org/0000-0001-8441-2755
Katsuhiro MikamiFaculty of Biology-Oriented Science and Technology, Kindai University, Kinokawa, Wakayama, Japan.
Takuto HatakeyamaDepartment of Orthopaedic Surgery, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan.
Masashi TakeuchiDepartment of Surgery, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan.
Kazumasa FukudaDepartment of Surgery, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan.
Akihisa UenoDivision of Diagnostic Pathology, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan.
Hajime OkitaDivision of Diagnostic Pathology, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan.
Hirofumi KawakuboDepartment of Surgery, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan.
Masaya NakamuraDepartment of Orthopaedic Surgery, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan.
Takeo NaguraDepartment of Orthopaedic Surgery, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan.
Yuko KitagawaDepartment of Surgery, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan.

Funding

2023 Kindai University Research Enchancement SR05JSPS KAKENHI JP24K15713
6 · The paper itself

Abstract

Tumor stiffness is drawing attention as a novel axis that is orthogonal to existing parameters such as pathological examination. We developed a new diagnostic method that focuses on differences in stiffness between tumor and normal tissue. This study comprised a clinical application of laser resonance frequency analysis (L-RFA) for diagnosing gastric cancer. L-RFA allows for precise and contactless evaluation of tissue stiffness. We used a laser to create vibrations on a sample's surface that were then measured using a vibrometer. The data were averaged and analyzed to enhance accuracy. In the agarose phantom experiments, a clear linear correlation was observed between the Young's modulus of the phantoms (0.34-0.71 MPa) and the summation of normalized vibration peaks (Score) in the 1950-4050 Hz range (R

Indexed as

Elastic ModulusLasersStomach NeoplasmsVibrationAgedFemaleGastrectomyHumansMaleMiddle AgedPhantoms, ImagingStomachagaroseendoscopic diagnosisresonance frequency analysisstomach neoplasmstumor stiffness

Identifiers

PMID39468628
PMCPMC11711037

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.