Evidence map›Paper›PMID 39468497›Full record

ArticleBMC oral health2024

A comparative quantitative assessment of 3D-printed PEKK and PEEK thin meshes in customized alveolar bone augmentation.

Xin-Rui Zhu, Chang Chen, Yun-Wei Hua, Xiao-Ying Xu, Ping Song, Rui-Yong Wang, Chen-Xi Wang

Abstract readComparative Study
In one paragraph

Article in BMC oral health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xin-Rui Zhu *Department of Stomatology, Beijing Haidian Hospital, Beijing, 100080, China.
Chang Chen *Department of Oral Healthcare, Chinese Stomatological Association, Beijing, 100081, China.
Yun-Wei HuaDepartment of Stomatology, Beijing Jishuitan Hospital, Capital Medical University, Beijing, 100035, China.
Xiao-Ying XuDepartment of Oral Implantology, Peking University School and Hospital of Stomatology, Beijing, 100081, China.
Ping SongShandong Kaisheng New Materials Co., Ltd., Zibo, 255185, China.
Rui-Yong WangDepartment of Stomatology, Beijing Haidian Hospital, Beijing, 100080, China. wangruiyong@163.com.
Chen-Xi WangDepartment of Stomatology, Beijing Haidian Hospital, Beijing, 100080, China. wcx-0604@163.com.

Funding

Science Foundation of Peking University School and Hospital of Stomatology PKUSS20210104
6 · The paper itself

Abstract

objectiveCustomized nonabsorbable membranes are widely used in severe alveolar bone defects and provide sufficient and precise regenerated bone tissue for subsequent dental implant placement. Although 3D-printed polyetheretherketone (PEEK) meshes have confirmed successful use in clinical cases, the performance of a PEEK mesh is not satisfactory. Compared with PEEK, polyetherketoneketone (PEKK) has better mechanical and processing properties. However, whether PEKK is suitable for making customized membranes remains unclear. The objectives of this study were (1) to evaluate the printing precision, surface characteristics, mechanical characteristics and biocompatibility of the PEKK mesh and (2) to compare the properties of the PEKK and PEEK meshes. MATERIALS AND

methodsBoth PEKK and PEEK meshes were designed and manufactured via additive manufacturing technology combined with computer-aided design (CAD). The printing precision was evaluated with a high-resolution extraoral scanner. The surface characteristics were evaluated with a contact angle system and three-dimensional optical microscopy. The mechanical characteristics were evaluated via three-point bending tests and tensile tests. The biocompatibility was evaluated with a CCK-8 assay, live/dead viability assay and qRT-PCT.

resultsCompared with the PEEK mesh, the PEKK mesh exhibited better control in terms of the thickness and aperture area. Both the PEKK mesh and the PEEK mesh had a hydrophobic surface, but the PEKK mesh had a smoother surface. Compared with the PEEK mesh, the PEKK mesh has better compression and tensile properties. Both the PEKK mesh and the PEEK mesh had good biocompatibility. The proliferation of cells on the PEKK mesh was slightly lower than that on the PEEK mesh.

conclusionsCompared with PEEK mesh, PEKK mesh has greater printing accuracy, smoother surfaces, better mechanical properties and similar biocompatibility and is expected to be used in the production of customized barrier membranes for the augmentation of severe bone defects. To ensure the stability of the mesh for clinical application, it is best to control the aperture diameter of the PEKK mesh to less than 2 mm with a thickness of 0.2 μm.

Indexed as

BenzophenonesBiocompatible MaterialsComputer-Aided DesignKetonesMaterials TestingPolyethylene GlycolsPolymersPrinting, Three-DimensionalSurgical MeshAlveolar Ridge AugmentationAnimalsHumansMiceSurface PropertiesTensile StrengthBenzophenonesBiocompatible MaterialsKetonespolyetheretherketonepolyetherketoneketonePolyethylene GlycolsPolymersAdditive manufacturing technologyCustomized alveolar bone augmentationPolyetheretherketone meshPolyetherketoneketone meshSevere bone defect

Identifiers

PMID39468497
PMCPMC11520829

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.