ArticleNature plants2024
Antagonistic CLE peptide pathways shape root meristem tissue patterning.
Article in Nature plants, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed.
- Pan-species genome-wide evolution of the RGF peptide gene family and its impact on adventitious root regeneration in apple.Horticulture research · 2026Article
- The ubiquitin code of receptor kinases in plants.Journal of integrative plant biology · 2026Review
- Crosstalk and reciprocal regulation of phosphorylation and ubiquitination mediated by receptor-like kinases and U-box E3 ligases during plant growth and environmental stress responses.Plant communications · 2026Review
- A CLE11b-CLE16 Signaling Relay Mediates Root-Shoot-Root Crosstalk for Drought Adaptation in Common Bean.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Ubiquitination of BAM1 attenuates CLE peptide-mediated signaling in the root apical meristem.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Wood-specific modification of glucuronoxylan can enhance growth in Populus.Journal of experimental botany · 2026Article
- Advances in the use of morphogenic regulators and peptide regenerating factors for boosting plant transformation and genome editing.Frontiers in plant science · 2026Review
- Small peptides play a key role as messengers in plant growth, development and abiotic stress resistance.Frontiers in plant science · 2026Review
- CLE pathways in plant development: recent advances and future perspectives.Journal of experimental botany · 2025Review
- Specificity of brassinosteroid perception and its integration at signaling crossroads in vascular development.The Plant journal : for cell and molecular biology · 2025Review
- Diversification of CLE expression patterns and nonmeristematic roles for CLAVATA receptor-like kinases in a moss.The New phytologist · 2025Article
- Research Progress of CLE and Its Prospects in Woody Plants.Plants (Basel, Switzerland) · 2025Review
- Receptor kinase pathway signal tuning through a nontranscriptional incoherent feedforward loop.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Peptide hormones in plants.Molecular horticulture · 2025Review
- Physiological, transcriptomic, and genomic analysis unravels the response of Tatary buckwheat root to high ammonium stress.Frontiers in plant science · 2025Article
- Functional Analysis ofInternational journal of molecular sciences · 2024Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Secreted CLAVATA3/EMBRYO SURROUNDING REGION (CLE) peptide ligands dimension the stem cell niche of Arabidopsis shoot meristems by signalling through redundant and cross-compensating CLAVATA1 (CLV1)-type receptor kinases. In the root meristem, the CLV1 homologues BARELY ANY MERISTEM 1 (BAM1) and BAM2 drive CLE13/16-mediated formative divisions that produce the ground tissue layers. Here we report that BAM1/2 are also required to initiate the vascular phloem lineage and that cross-compensation between CLV1-type receptors as observed in the shoot does not operate similarly in the root. Rather, we find that BAM3-mediated CLE45 signalling antagonizes BAM1/2-mediated CLE11/12/13 signalling in the phloem initials but not in the ground tissue. We further observe spatiotemporally contrasting CLE signalling requirements for phloem initiation and differentiation, which are shaped by the SHORT ROOT (SHR) pathway. Our findings thus suggest an intricate quantitative interplay between distinct and antagonistic CLE signalling pathways that organizes tissue layer formation in the Arabidopsis root meristem.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.