SynthesisScientific reports2024
Normal ranges of left atrial phasic strains and strain rates by 2D speckle-tracking echocardiography in pediatrics: a systematic review and meta-analysis.
Synthesis in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed.
- Ventricular Remodeling and Subclinical Dysfunction in Pediatric Obesity: Echocardiographic Links to Weight and Abdominal Fat.Pediatric cardiology · 2026Article
- Applications of speckle tracking echocardiography in paediatric and congenital heart disease: an expert consensus paper from AEPC Imaging Working Group.European heart journal. Imaging methods and practice · 2026Article
- Evaluation of myocardial function by strain echocardiography in cats with hypertrophic cardiomyopathy phenotypes.Veterinary world · 2026Article
- Myocardial Deformation Analysis in Congenital Aortic Valve Stenosis: Comparison Across Clinical Phenotypes in Children.Pediatric cardiology · 2026Article
- Left atrial strain on 2D-STE in pediatric dilated cardiomyopathy.Echo research and practice · 2026Article
- Left atrium dysfunction and dyssynchrony in pediatric patients with Wolff-Parkinson-White syndrome assessed using speckle-tracking echocardiography.Heart and vessels · 2026Article
- Left Atrial Strain in Pediatric Cardiology: Evidence to Date and Future Directions.Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography · 2026Review
- Left atrial strain reveals subclinical dysfunction in children after successful coarctation repair.PloS one · 2026Observational
- Pediatric Echocardiographic Nomograms: Twenty Years of Advances-Do We Now Have a Complete and Reliable Tool, or Are Gaps Still Present? An Up-to-Date Review.Journal of clinical medicine · 2025Review
- Normal Values for Speckle-Tracking Echocardiography in Children: A Review, Update, and Guide for Clinical Use of Speckle-Tracking Echocardiography in Pediatric Patients.Journal of clinical medicine · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Establishing normal values of left atrial (LA) phasic strains and strain rates is essential for distinguishing between normal and abnormal functions, determining the degree of abnormality, and understanding the clinical significance of reported values in pediatrics. This meta-analysis aimed to establish normal values of two-dimensional speckle-tracking echocardiography (2DSTE)-derived LA phasic strains and strain rates in the pediatric population and identify the sources of inter-study heterogeneity for these values. A comprehensive search of PubMed, Scopus, and Embase databases was conducted using keywords such as "left atrial/left atrium," "strain/speckle/deformation," and "echocardiography" combined with pediatric age categories. Inclusion criteria comprised English-language human studies involving healthy subjects under 18 years of age. Subjects were categorized as neonates (up to 1 month), infants (1-12 months), and children (1-18 years). A random-effects model was applied to determine 2DSTE-derived LA strains and strain rates, and a meta-regression analysis was performed to investigate inter-study heterogeneity. Our analysis included 17 studies involving 1448 healthy subjects. For children, the mean values of LA strains during the reservoir, conduit, and contraction phases were 47.3% (95% CI 42.5-52.1%), 32.8% (95% CI 27.8-37.8%), and 12% (95% CI 10.0-14.1%), respectively. The mean values for LA strain rates were 2.4 s
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.