Evidence map›Paper›PMID 39468178›Full record

ArticleScientific reports2024

Prevalence of steatotic liver disease (MASLD, MetALD, ALD) and clinically significant fibrosis in US adolescents : Authors' name.

Guang-Xia Shi, Yun-Song Qian, Chun-Mei Jiang, Zhen-Zhen Liu, Xi Yang, Yi-Wen Xu, Su-Su Jin, Jin-Guo Chu, Guo-Qing Qian, Nai-Bin Yang

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Article
  3. Observational
  4. Review
  5. Review
  6. Rethinking risk indices in pediatric MASLD.JHEP reports : innovation in hepatology · 2025
    Article
  7. MetALD: New Perspectives on an Old Overlooked Disease.Liver international : official journal of the International Association for the Study of the Liver · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Guang-Xia Shi *Department of Hepatology and Infectious Diseases, the First Affiliated Hospital of Ningbo University, Ningbo, Zhejiang, China.
Yun-Song Qian *Department of Hepatology, Ningbo No.2 Hospital, Ningbo, Zhejiang, China.
Chun-Mei Jiang *Department of Infectious Diseases, the People's Hospital of Longhua, Shenzhen, Guangdong, China.
Zhen-Zhen Liu *Department of Infectious Diseases, the People's Hospital of Longhua, Shenzhen, Guangdong, China.
Xi YangDepartment of Clinical nutrition, the First Affiliated Hospital of Ningbo University, Ningbo, Zhejiang, China.
Yi-Wen XuDepartment of Hepatology and Infectious Diseases, the First Affiliated Hospital of Ningbo University, Ningbo, Zhejiang, China.
Su-Su JinDepartment of Hepatology and Infectious Diseases, the First Affiliated Hospital of Ningbo University, Ningbo, Zhejiang, China.
Jin-Guo ChuDepartment of Hepatology and Infectious Diseases, the First Affiliated Hospital of Ningbo University, Ningbo, Zhejiang, China. chujg@126.com.
Guo-Qing QianDepartment of Hepatology and Infectious Diseases, the First Affiliated Hospital of Ningbo University, Ningbo, Zhejiang, China. guoqing.qian@foxmail.com.
Nai-Bin YangDepartment of Hepatology and Infectious Diseases, the First Affiliated Hospital of Ningbo University, Ningbo, Zhejiang, China. mafld2021@163.com.

Funding

the Medical Health Science and Technology Project of Zhejiang Provincial Health Commission 2019KY579the Medical Health Science and Technology Project of Zhejiang Provincial Health Commission 2024KY1530 and 2021KY989Zhejiang University and Ningbo First Hospital docking discipline general medicine zd2020018
6 · The paper itself

Abstract

We aim to evaluate the prevalence of steatotic liver disease (SLD) in United States (US) adolescents and explore whether metabolic dysfunction-associated steatotic liver disease (MASLD) can identify individuals with clinically significant fibrosis (CSF) in this study. The prevalence of SLD and its categories, including MASLD, metabolic dysfunction and alcohol associated liver disease (MetALD), alcohol related liver disease (ALD) and other SLD were determined. Weighted multivariable logistic regression analysis was conducted to evaluate the association between MASLD and CSF in adolescents with SLD. Among the total 1,446 US adolescents, SLD was present in 291 (20.1%) of individuals, including 260 (17.9%) for MASLD, 9 (0.6%) for MetALD and 5 (0.3%) for ALD. Only 58 (4%) had CSF. Patients with SLD showed a higher prevalence of CSF (9.6% vs. 2.6%, p < 0.001). Among patients with SLD, 89.3% met the MASLD criteria. The risk of CSF in patients with MASLD was not significantly different (odds ratio [OR] = 1.07, 95% confidence interval [CI] = 0.30-3.83, p = 0.9180) compared with those without MASLD. MASLD was met by most of the US adolescents with SLD. Moreover, MASLD was not associated with higher prevalence of CSF among adolescents with SLD.

Indexed as

Fatty LiverLiver CirrhosisAdolescentFemaleHumansLiver Diseases, AlcoholicMalePrevalenceUnited StatesAdolescentFibrosisMASLDSLD

Identifiers

PMID39468178
PMCPMC11519858

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.