Evidence map›Paper›PMID 39468146›Full record

ArticleNature communications2024

Temporal dynamics of nucleus accumbens neurons in male mice during reward seeking.

Terra A Schall, King-Lun Li, Xiguang Qi, Brian T Lee, William J Wright, Erin E Alpaugh, Rachel J Zhao, Jianwei Liu, Qize Li, Bo Zeng and 6 more

Abstract read
In one paragraph

Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Refinement of Nucleus Accumbens Neuronal Dynamics during Cocaine Self-Administration Training.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Terra A Schall *Department of Neuroscience, University of Pittsburgh, Pittsburgh, PA, 15260, USA.
King-Lun Li *Department of Neuroscience, University of Pittsburgh, Pittsburgh, PA, 15260, USA.
Xiguang Qi *Department of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, PA, 15213, USA.ORCID 0000-0003-0325-2118
Brian T LeeSchool of Computer Science, Carnegie Mellon University, Pittsburgh, PA, 15213, USA.ORCID 0009-0004-4266-1170
William J WrightDepartment of Neuroscience, University of Pittsburgh, Pittsburgh, PA, 15260, USA.ORCID 0000-0003-0835-6362
Erin E AlpaughDepartment of Neuroscience, University of Pittsburgh, Pittsburgh, PA, 15260, USA.
Rachel J ZhaoDepartment of Neuroscience, University of Pittsburgh, Pittsburgh, PA, 15260, USA.
Jianwei LiuDepartment of Industrial Engineering, Swanson School of Engineering, University of Pittsburgh, Pittsburgh, PA, 15261, USA.
Qize LiDepartment of Neuroscience, University of Pittsburgh, Pittsburgh, PA, 15260, USA.
Bo ZengDepartment of Industrial Engineering, Swanson School of Engineering, University of Pittsburgh, Pittsburgh, PA, 15261, USA.
Lirong WangDepartment of Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, PA, 15213, USA.
Yanhua H HuangDepartment of Psychiatry, University of Pittsburgh, Pittsburgh, PA, 15260, USA.ORCID 0000-0003-1770-0196
Oliver M SchlüterDepartment of Neuroscience, University of Pittsburgh, Pittsburgh, PA, 15260, USA.ORCID 0000-0001-8958-5815
Eric J NestlerNash Family Department of Neuroscience and Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.ORCID 0000-0002-7905-2000
Edward H NiehDepartment of Pharmacology, University of Virginia, Charlottesville, VA, 22903, USA.
Yan DongDepartment of Neuroscience, University of Pittsburgh, Pittsburgh, PA, 15260, USA. yandong@pitt.edu.ORCID 0000-0003-0016-9028

Funding

Predoctorial Training in Basic NeuroscienceT32NS007433 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MERINEY, STEPHEN D · 1998 to 2022
$8.0M
Glial-mediated synaptic remodeling in drug addictionR01DA040620 · NIDA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Yan Dong, ERIC J. NESTLER · 2016 to 2026
$5.3M
Cocaine-induced adaptation in NMDA receptorsR37DA023206 · NIDA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Yan Dong · 2018 to 2026
$3.9M
Cocaine-induced Adaptation in NMDA Receptors in Nucleus AccumbensR01DA023206 · NIDA · WASHINGTON STATE UNIVERSITY · PI DONG, YAN · 2008 to 2017
$3.0M
Sleep regulates drug relapse and addictionR01DA046491 · NIDA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HUANG, YANHUA H · 2019 to 2023
$1.8M
Cellular and Behavioral Function of Astrocytic Dopamine SignalingR01DA060868 · NIDA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Yan Dong · 2024 to 2026
$1.3M
Characterizing the underlying population code to understand the functional organization of the hippocampus and the lateral hypothalamusR00DA053388 · NIDA · UNIVERSITY OF VIRGINIA · PI NIEH, HORNG-AN EDWARD · 2023 to 2025
$747k
Interaction of Glutamatergic Inputs to Nucleus AccumbensR21DA051010 · NIDA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI DONG, YAN · 2020 to 2021
$431k
Characterizing the underlying population code to understand the functional organization of the hippocampus and the lateral hypothalamusK99DA053388 · NIDA · PRINCETON UNIVERSITY · PI NIEH, HORNG-AN EDWARD · 2022 to 2023
$307k
NIDA NIH HHS K99 DA053388NIDA NIH HHS R00 DA053388NIDA NIH HHS R01 DA023206NIDA NIH HHS R01 DA040620NIDA NIH HHS R01 DA046491NIDA NIH HHS R01 DA060868NIDA NIH HHS R21 DA051010NIDA NIH HHS R37 DA023206NINDS NIH HHS T32 NS007433U.S. Department of Health & Human Services | NIH | National Institute on Drug Abuse (NIDA) DA23206U.S. Department of Health & Human Services | NIH | National Institute on Drug Abuse (NIDA) DA40620U.S. Department of Health & Human Services | NIH | National Institute on Drug Abuse (NIDA) DA46491U.S. Department of Health & Human Services | NIH | National Institute on Drug Abuse (NIDA) DA51010U.S. Department of Health & Human Services | NIH | National Institute on Drug Abuse (NIDA) DA53388U.S. Department of Health & Human Services | NIH | National Institute on Drug Abuse (NIDA) DA60868
6 · The paper itself

Abstract

The nucleus accumbens (NAc) regulates reward-motivated behavior, but the temporal dynamics of NAc neurons that enable "free-willed" animals to obtain rewards remain elusive. Here, we recorded Ca

Indexed as

NeuronsNucleus AccumbensReceptors, Dopamine D1Receptors, Dopamine D2RewardAnimalsBehavior, AnimalCalciumMaleMiceMice, Inbred C57BLMotivationSucroseTime FactorsCalciumReceptors, Dopamine D1Receptors, Dopamine D2Sucrose

Identifiers

PMID39468146
PMCPMC11519475

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.