Evidence map›Paper›PMID 39467993›Full record

ArticleCJEM2024

Safety and efficiency of implementation of high-sensitivity troponin T in the assessment of emergency department patients with cardiac chest pain.

Frank X Scheuermeyer, Andre Mattman, Karin Humphries, Krishnan Ramanathan, Kendeep Kaila, Peter Dodek, Brian Grunau, Eric Grafstein, Grant Innes, Jim Christenson

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in CJEM, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Frank X ScheuermeyerDepartment of Emergency Medicine, St Paul's Hospital and the University of British Columbia, Vancouver, BC, Canada. frank.scheuermeyer@gmail.com.ORCID 0000-0001-9517-9258
Andre MattmanDepartment of Pathology and Laboratory Medicine, St Paul's Hospital and the University of British Columbia, Vancouver, BC, Canada.
Karin HumphriesCenter for Advancing Health Outcomes, Vancouver, BC, Canada.
Krishnan RamanathanDivision of Cardiology, Department of Medicine, St Paul's Hospital and the University of British Columbia, Vancouver, BC, Canada.
Kendeep KailaDivision of Cardiology, Department of Medicine, St Paul's Hospital and the University of British Columbia, Vancouver, BC, Canada.
Peter DodekDivision of Critical Care Medicine, Department of Medicine, St Paul's Hospital and the University of British Columbia, Vancouver, BC, Canada.
Brian GrunauDepartment of Emergency Medicine, St Paul's Hospital and the University of British Columbia, Vancouver, BC, Canada.
Eric GrafsteinDepartment of Emergency Medicine, St Paul's Hospital and the University of British Columbia, Vancouver, BC, Canada.
Grant InnesDepartment of Emergency Medicine, University of Calgary, Calgary, AB, Canada.
Jim ChristensonDepartment of Emergency Medicine, St Paul's Hospital and the University of British Columbia, Vancouver, BC, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFor emergency department (ED) patients with cardiac chest pain, introduction of high-sensitivity troponin (hsTnT) pathways has been associated with reductions in length of stay of less than 1 h.

methodsAt two urban Canadian sites, we introduced hsTnT on January 26, 2016. While the prior diagnostic algorithm required troponin testing at 0 and 6 h, serial hsTnT serial testing was conducted at 0 and 3 h. We identified consecutive patients who presented with cardiac chest pain from January 1, 2015, to March 31, 2017, along with 30-day outcomes. The primary outcome was a missed 30-day major adverse cardiac event, (MACE) defined as death, revascularization, or readmission for myocardial infarction occurring in a patient-discharged home with a minimizing diagnosis and without cardiac-specific follow-up. Secondary outcomes included admission rate, ED length of stay, and MACE. We compared pre- and post- implementation periods using descriptive methods and repeated this analysis in patients with noncardiac chest pain.

resultsWe collected 5585 patients with cardiac chest pain, (2678 pre- and 2907 post-introduction) and 434 had (7.8%, 95% CI 7.1 to 8.5%) MACE, with 1 missed MACE. (0.2%, 95% CI 0.04 to 1.3%). Admission rate was stable at 24.1% pre- and 23.7% while median length of stay decreased from 464 to 285 min, a difference of 179 min. (95% CI 61 to 228 min). For 11,611 patients with noncardiac chest pain, admission rate (9%) and length of stay (191 versus 193 min) remained constant.

conclusionsImplementation of hsTnT for evaluation of ED chest pain patients was safe and associated with a 3-h decrease in length of stay.

Indexed as

Chest PainEmergency Service, HospitalTroponin TAgedBiomarkersCanadaFemaleHumansLength of StayMaleMiddle AgedMyocardial InfarctionRetrospective StudiesBiomarkersTroponin TAcute coronary syndromeChest painQuality improvement

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.