Evidence map›Paper›PMID 39467940›Full record

SynthesisSports medicine - open2024

The Effects of Aerobic Exercise Training on Testosterone Concentration in Individuals Who are Obese or Have Type 2 Diabetes: A Systematic Review and Meta-Analysis.

Rhiannon Healy, Rhiannon Patten, Carlie Bauer, Mary N Woessner, Matthew Bourke, Mathis Grossmann, Itamar Levinger

Abstract readSystematic Review
In one paragraph

Synthesis in Sports medicine - open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Rhiannon HealyInstitute for Health and Sport (IHES), Victoria University, PO Box 14428, Melbourne, Australia.
Rhiannon PattenInstitute for Health and Sport (IHES), Victoria University, PO Box 14428, Melbourne, Australia.
Carlie BauerInstitute for Health and Sport (IHES), Victoria University, PO Box 14428, Melbourne, Australia.
Mary N WoessnerInstitute for Health and Sport (IHES), Victoria University, PO Box 14428, Melbourne, Australia.
Matthew BourkeSchool of Human Movement and Nutrition Sciences, The University of Queensland, Brisbane, QLD, Australia.
Mathis GrossmannUniversity of Melbourne Austin Health, Heidelberg, VIC, Australia.
Itamar LevingerInstitute for Health and Sport (IHES), Victoria University, PO Box 14428, Melbourne, Australia. itamar.levinger@vu.edu.au.ORCID http://orcid.org/0000-0001-9194-2033

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundObesity and type 2 diabetes (T2D) are associated with alterations in testosterone concentrations. While evidence indicates that aerobic training can influence testosterone in healthy populations or females with hyperandrogenism, its impact in individuals with obesity or T2D remains unclear. Thus, the aim of this study was to investigate whether aerobic training can influence circulating testosterone concentrations in individuals with obesity or T2D.

methodsEBSCOhost (CINAHL, MEDLINE, SPORTDiscus), PubMed and Embase were searched for articles published until August 2023. Eligible articles included individuals with obesity or T2D that underwent an aerobic exercise intervention with testosterone concentrations measured at baseline and post intervention. Two reviewers independently screened the seven articles included in this meta-analysis and conducted data extraction and risk of bias assessments.

resultsA total of 103 participants (62 men / 41 women) from three randomised controlled trials and four non-randomised controlled trials were included. Effect sizes were computed with random effects models. Aerobic exercise moderately increased testosterone concentrations in men (g = 0.565, 95% CI = 0.307 to 0.822, p < 0.001), but had no significant effect in women (g = -0.523, 95% CI = -1.541, 0.496, p = 0.314). Aerobic exercise had no significant effect on sex hormone-binding globulin or markers of insulin sensitivity (p > 0.05).

conclusionsAerobic training may be used to increase testosterone concentrations in men with obesity or T2D, but potentially has no influence in women. Given the low number of studies, further studies investigating the effect of exercise on circulating sex hormones in men and women with obesity or T2D are needed.

Indexed as

Aerobic exerciseInsulin sensitivityObesitySex hormone binding globulinTestosteroneType 2 diabetes

Identifiers

PMID39467940
PMCPMC11519272

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.