Evidence map›Paper›PMID 39467914›Full record

ArticleAbdominal radiology (New York)2025

Non-contrast-enhanced MR-angiography of the abdominal arteries: intraindividual comparison between relaxation-enhanced angiography without contrast and triggering (REACT) and 4D contrast-enhanced MR-angiography.

Carsten Gietzen, Jan Paul Janssen, Lukas Görtz, Kenan Kaya, Thorsten Gietzen, Roman Johannes Gertz, Henry Pennig, Katharina Seuthe, David Maintz, Philip S Rauen and 3 more

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Abdominal radiology (New York), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Carsten GietzenFaculty of Medicine and University Hospital Cologne, Institute for Diagnostic and Interventional Radiology, University of Cologne, Kerpener Straße 62, 50937, Cologne, Germany. Carsten.gietzen@uk-koeln.de.
Jan Paul JanssenFaculty of Medicine and University Hospital Cologne, Institute for Diagnostic and Interventional Radiology, University of Cologne, Kerpener Straße 62, 50937, Cologne, Germany.
Lukas GörtzFaculty of Medicine and University Hospital Cologne, Institute for Diagnostic and Interventional Radiology, University of Cologne, Kerpener Straße 62, 50937, Cologne, Germany.
Kenan KayaFaculty of Medicine and University Hospital Cologne, Institute for Diagnostic and Interventional Radiology, University of Cologne, Kerpener Straße 62, 50937, Cologne, Germany.
Thorsten GietzenDepartment of Cardiology, Faculty of Medicine and University Hospital Cologne, Heart Center, University of Cologne, Cologne, Germany.
Roman Johannes GertzFaculty of Medicine and University Hospital Cologne, Institute for Diagnostic and Interventional Radiology, University of Cologne, Kerpener Straße 62, 50937, Cologne, Germany.
Henry PennigDepartment of Orthopedics and Trauma Surgery, University Hospital Bonn, Bonn, Germany.
Katharina SeutheDepartment of Cardiology, Faculty of Medicine and University Hospital Cologne, Heart Center, University of Cologne, Cologne, Germany.
David MaintzFaculty of Medicine and University Hospital Cologne, Institute for Diagnostic and Interventional Radiology, University of Cologne, Kerpener Straße 62, 50937, Cologne, Germany.
Philip S RauenFaculty of Medicine and University Hospital Cologne, Institute for Diagnostic and Interventional Radiology, University of Cologne, Kerpener Straße 62, 50937, Cologne, Germany.
Thorsten PersigehlFaculty of Medicine and University Hospital Cologne, Institute for Diagnostic and Interventional Radiology, University of Cologne, Kerpener Straße 62, 50937, Cologne, Germany.
Kilian WeissPhilips GmbH, Hamburg, Germany.
Lenhard PennigFaculty of Medicine and University Hospital Cologne, Institute for Diagnostic and Interventional Radiology, University of Cologne, Kerpener Straße 62, 50937, Cologne, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate Relaxation-Enhanced Angiography without Contrast and Triggering (REACT), a novel 3D isotropic flow-independent non-contrast-enhanced magnetic resonance angiography (non-CE-MRA) for imaging of the abdominal arteries, by comparing image quality and assessment of vessel stenosis intraindidually with 4D CE-MRA.

methodsThirty patients (mean age 35.7 ± 16.8 years; 20 females) referred for the assessment of the arterial abdominal vasculature at 3 T were included in this retrospective, single-centre study. The protocol comprised both 4D CE-MRA and REACT (navigator-triggering, Compressed SENSE factor 10, nominal scan time 02:54 min, and reconstructed voxel size 0.78 × 0.78 × 0.85  mm

resultsREACT had a total acquisition time of 5:36 ± 00:40 min, while 4D CE-MRA showed a total acquisition time (including the native scan and bolus tracking sequence) of 3:45 ± 00:59 min (p = 0.001). Considering 4D CE-MRA as the reference standard, REACT achieved a sensitivity of 87.5% and specificity of 100.0% for relevant (≥ 50%) stenosis while detecting 89.5% of all vascular findings other than stenosis. For all vessels combined, subjective vessel quality was slightly higher in 4D CE-MRA (3.0 [IQR: 2.0; 4.0.]; P = 0.040), although comparable to REACT (3.0 [IQR: 2.0; 3.5]).

conclusionIn a short scan time of about 5 min, REACT provides good diagnostic performance for detection of relevant stenoses, variants, and vascular findings of the abdominal arteries, while yielding to 4D CE-MRA comparable image quality.

Indexed as

AbdomenImage EnhancementImaging, Three-DimensionalMagnetic Resonance AngiographyAdultAgedContrast MediaFemaleHumansMaleMiddle AgedRetrospective StudiesContrast MediaAbdominal vessel imagingCompressed SENSEContrast-enhanced magnetic resonance angiographyRelaxation-enhanced angiography without contrast and triggeringVisceral arteries

Identifiers

PMID39467914
PMCPMC11947023

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.