Evidence map›Paper›PMID 39467873›Full record

ArticleDiabetologia2025

Autoimmune diseases and the risk and prognosis of latent autoimmune diabetes in adults.

Cornelia Santoso, Yuxia Wei, Emma Ahlqvist, Tiinamaija Tuomi, Sofia Carlsson

Abstract read
In one paragraph

Article in Diabetologia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Observational
  3. Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Cornelia SantosoInstitute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden. cornelia.santoso@ki.se.ORCID http://orcid.org/0000-0002-5534-4404
Yuxia WeiInstitute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.ORCID http://orcid.org/0000-0002-3390-0844
Emma AhlqvistDepartment of Clinical Sciences in Malmö, Clinical Research Centre, Lund University, Malmö, Sweden.ORCID http://orcid.org/0000-0002-6513-2384
Tiinamaija TuomiDepartment of Clinical Sciences in Malmö, Clinical Research Centre, Lund University, Malmö, Sweden.ORCID http://orcid.org/0000-0002-8306-6202
Sofia CarlssonInstitute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.ORCID http://orcid.org/0000-0002-9497-2331

Funding

China Scholarship Council student number 202006010041Swedish Diabetes foundation DIA2022-735Swedish Research Council 2018-03035Swedish Research Council 2022-00811Swedish Research Council for Health, Working Life and Welfare 2018-00337Swedish Research Council for Health, Working Life and Welfare FORTE
6 · The paper itself

Abstract

aims/hypothesisThe aim of this study was to clarify the impact of autoimmune disease (AD) comorbidity on the risk and prognosis of latent autoimmune diabetes in adults (LADA).

methodsWe used data from a Swedish study comprising newly diagnosed cases of LADA (n=586, stratified into LADA

resultsIndividuals with ADs exhibit an increased susceptibility to LADA (OR 1.70; 95% CI 1.36, 2.13), particularly those with thyroid dysfunction (OR 1.88; 95% CI 1.38, 2.56), inflammatory bowel disease (OR 1.78; 95% CI 1.00, 3.16) or vitiligo (OR 3.91; 95% CI 1.93, 7.94), with stronger associations being observed for the LADA CONCLUSIONS/

interpretationWe confirm that several common ADs confer an excess risk of LADA, especially LADA with higher GADA levels, but having such a comorbidity does not appear to affect the risk of diabetic retinopathy.

Indexed as

Autoimmune DiseasesLatent Autoimmune Diabetes in AdultsAdultAgedAutoantibodiesCase-Control StudiesDiabetes Mellitus, Type 2Diabetic RetinopathyFemaleHumansMaleMiddle AgedPrognosisRisk FactorsSwedenAutoantibodiesAutoimmune diseaseDiabetic retinopathyEpidemiologyLatent autoimmune diabetes in adultsPrognosisRisk factor

Identifiers

PMID39467873
PMCPMC11732938

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.