Evidence map›Paper›PMID 39467825›Full record

ArticleNursing in critical care2025

Clinical trial protocol for continuous glucose monitoring in critical care at Hospital Clinic of Barcelona (CGM-UCI23).

Marc Pañero-Moreno, Eva Maria Guix-Comellas, Alberto Villamor-Ordozgoiti

Registry-linked trialAbstract readClinical Trial Protocol
In one paragraph

Article in Nursing in critical care, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07687368 (Continuous Glucose Monitoring in Critically Ill Patients), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07687368 nacompletednot on this map

Continuous Glucose Monitoring in Critically Ill Patients: a Randomized Controlled Trial in the Intensive Care Units of Hospital Clínic of Barcelona (CGM-UCI23)

TypeinterventionalSponsorInstitut d'Investigacions Biomèdiques August Pi i SunyerRan2025 to 2026Enrolled400ConditionsCritical Care Nursing, Critical Illness, Critical Care, Intensive Care, HyperglycaemiaArmsContinuous Glucose Monitoring, Conventional Glucose Measurement
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Marc Pañero-MorenoCritical Care Nurse, Hospital Clinic of Barcelona, Barcelona, Catalonia, Spain.ORCID https://orcid.org/0009-0006-9077-4350
Eva Maria Guix-ComellasPhD Programme in Medicine and Translational Research, University of Barcelona, Barcelona, Catalonia, Spain.ORCID https://orcid.org/0000-0001-9866-7265
Alberto Villamor-OrdozgoitiBarcelona Clinical Research Foundation - August Pi i Sunyer Biomedical Research Institute (FRCB-IDIBAPS), Barcelona, Catalonia, Spain.ORCID https://orcid.org/0000-0002-3108-349X

Funding

Catalan Society of Intensive and Critical Medicine (SOCMIC)Dexcom HOS-2023-021Official College of Nurses of Barcelona (COIB) PR-687/2024
6 · The paper itself

Abstract

backgroundHyperglycaemia is common in intensive care units (ICUs), with a prevalence of up to 86.2%, increasing mortality. Technology has evolved towards continuous glucose monitoring (CGM), and its use in ICUs began especially during the coronavirus pandemic (COVID-19). Various studies have evaluated the reliability of CGM, indicating that it is safe for use in critically ill patients.

aimThe aim of this study was to compare the use of CGM with point-of-care glucose (POC-G) testing in ICU. Specific objectives include evaluating the glycaemic control, the frequency of POC-G measurements, the incidence of hyperglycaemia, hypoglycaemia and morbidity and mortality at 90 days. STUDY

designAn experimental, controlled and randomized clinical trial with a single-blind design will be conducted at Hospital Clinic of Barcelona (HCB). A sample size of 376 participants will be recruited and randomly assigned to two groups: an experimental group, where glycaemic management will be based on CGM; and a control group, where glucose will be managed through POC-G testing, with a blinded CGM.

resultsThe primary variable considered will be time in range (TIR), with secondary outcomes including, time above range (TAR), time below range (TBR), number of POC-G measurements, incidence of hyperglycaemia and hypoglycaemia, and mortality. Hypothesis testing will use the Kolmogorov-Smirnov test to assess data normality, with appropriate statistical tests applied, considering a p-value <.05. RELEVANCE TO CLINICAL PRACTICE: The results obtained will help us understand the impact of CGM on critically ill patients. CGM could potentially reduce the workload of nurses and improve the efficiency of decision-making by the ICU team, enabling early identification and treatment of glucose complications, thereby enhancing safety. Patient safety, a reduction in patient fingerstick and a decreased care burden are the criteria that add value to this research.

Indexed as

Blood GlucoseCOVID-19Critical CareHyperglycemiaContinuous Glucose MonitoringCritical IllnessHumansHypoglycemiaIntensive Care UnitsMonitoring, PhysiologicPoint-of-Care SystemsRandomized Controlled Trials as TopicSingle-Blind MethodSpainBlood Glucosecontinuous glucose monitoringcritical care nursingcritical illnesshyperglycaemiaintensive care

Identifiers

PMID39467825
PMCPMC12096265

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.