Evidence map›Paper›PMID 39467714›Full record

ArticleThe Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology2024

Protective effect of 6'-Sialyllactose on LPS-induced macrophage inflammation

Hami Yu, Yujin Jin, Hyesu Jeon, Lila Kim, Kyung-Sun Heo

Abstract read
In one paragraph

Article in The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Amorfrutin A ameliorates cerebral ischemia/reperfsion injuryThe Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2025
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hami YuCollege of Pharmacy and Institute of Drug Research and Development, Chungnam National University, Daejeon 34134, Korea.
Yujin JinCollege of Pharmacy and Institute of Drug Research and Development, Chungnam National University, Daejeon 34134, Korea.
Hyesu JeonDepartment of Cancer AI & Digital Health, National Cancer Center, Goyang 10408, Korea.
Lila KimGeneChem Inc., Daejeon 34025, Korea.
Kyung-Sun HeoCollege of Pharmacy and Institute of Drug Research and Development, Chungnam National University, Daejeon 34134, Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Macrophages play a central role in cardiovascular diseases, like atherosclerosis, by accumulating in vessel walls and inducing sustained local inflammation marked by the release of chemokines, cytokines, and matrix-degrading enzymes. Recent studies indicate that 6'-sialyllactose (6'-SL) may mitigate inflammation by modulating the immune system. Here, we examined the impact of 6'-SL on lipopolysaccharide (LPS)-induced acute inflammation using RAW 264.7 cells and a mouse model.

Indexed as

6’-sialyllactoseAcute inflammationOxidative stress

Identifiers

PMID39467714
PMCPMC11519721

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.