Evidence map›Paper›PMID 39467102›Full record

ArticleBrain and behavior2024

Effects of Goreisan in the Perioperative Period of Subthalamic Deep Brain Stimulation in Parkinson's Disease.

Hiroyuki Kajikawa, Keita Matsuura, Yuichiro Ii, Ken-Ichi Tabei, Naoko Nakamura, Hidehiro Ishikawa, Yamato Nishiguchi, Kana Matsuda, Ken Kagawa, Naoki Ichikawa and 2 more

Abstract read
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In one paragraph

Article in Brain and behavior, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Hiroyuki KajikawaDepartment of Neurology, Graduate School of Medicine, Mie University, Mie, Japan.
Keita MatsuuraDepartment of Neurology, Graduate School of Medicine, Mie University, Mie, Japan.ORCID https://orcid.org/0000-0002-4073-2340
Yuichiro IiDepartment of Neuroimaging and Pathophysiology, Mie University School of Medicine, Mie, Japan.ORCID https://orcid.org/0000-0002-3254-7743
Ken-Ichi TabeiSchool of Industrial Technology, Advanced Institute of Industrial Technology, Tokyo Metropolitan Public University Corporation, Tokyo, Japan.ORCID https://orcid.org/0000-0002-3969-9184
Naoko NakamuraDepartment of Neurology, Graduate School of Medicine, Mie University, Mie, Japan.
Hidehiro IshikawaDepartment of Neurology, Graduate School of Medicine, Mie University, Mie, Japan.ORCID https://orcid.org/0000-0002-3077-7262
Yamato NishiguchiDepartment of Neurology, Graduate School of Medicine, Mie University, Mie, Japan.ORCID https://orcid.org/0000-0002-8034-2670
Kana MatsudaDepartment of Dementia Prevention and Therapeutics, Mie University Graduate School of Medicine, Mie, Japan.ORCID https://orcid.org/0000-0002-5586-2340
Ken KagawaDepartment of Neurorolgy, Suzukakaisei Hospital, Mie, Japan.
Naoki IchikawaDepartment of Neurosurgery, Suzukakaisei Hospital, Mie, Japan.
Tomohiro ArakiDepartment of Neurosurgery, Suzukakaisei Hospital, Mie, Japan.
Akihiro ShindoDepartment of Neurology, Graduate School of Medicine, Mie University, Mie, Japan.ORCID https://orcid.org/0000-0002-1006-4943

Funding

Japan Society for the Promotion of Science JP19K17031
6 · The paper itself

Abstract

introductionPatients with Parkinson's disease (PD) may benefit from deep brain stimulation (DBS). Perifocal brain edema sometimes occurs after DBS surgery, but it is transient and does not affect the final prognosis. Transient deterioration of cognitive function has been reported in patients with frontal edema in the first postoperative week. This study aimed to investigate the effect of Goreisan in preventing edematous changes after DBS and determine the influence of edema on cognition.

methodsWe included 29 patients with PD who underwent bilateral subthalamic nucleus (STN) DBS and who were divided into 2 groups: those using (11 patients) and those not using Goreisan (18 patients). At 1 week postoperatively, all patients underwent magnetic resonance imaging. We measured the volume of edema either in the frontal white matter or STN on fluid-attenuated inversion recovery (FLAIR) images. Finally, brain edema, motor function, and cognitive function were compared between the groups with and without Goreisan.

resultsIn the FLAIR image 1 week postoperatively, the average postoperative frontal subcortical edema (FE) volume of the group with Goreisan was significantly lower than that without Goreisan (2249 ± 2186 mm

conclusionsFE after DBS surgery may be alleviated using Goreisan. SE and preoperative MMSE scores were associated with MMSE scores 1 week postoperatively.

trial registrationNot applicable.

Indexed as

Deep Brain StimulationParkinson DiseaseSubthalamic NucleusAgedBrain EdemaCognitionFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedPerioperative Periodbrain edemadeep brain stimulationGoreisanParkinson's disease

Identifiers

PMID39467102
PMCPMC11516107

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.