ArticleRenal failure2024
Association between albumin-corrected anion gap and kidney function in individuals with hypertension - NHANES 2009-2016 cycle.
Article in Renal failure, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Machine learning-based risk assessment of neonatal perinatal adverse outcomes of anemia during pregnancy: a modeling study.BMC medical informatics and decision making · 2026Article
- Hypertension-Induced Renal Injury: From Pathophysiology to Therapeutic Perspectives.Biomedicines · 2026Review
- Article
- The prognostic value of albumin-corrected anion gap for major adverse cardiac events in chronic kidney disease patients undergoing percutaneous coronary intervention.Frontiers in cardiovascular medicine · 2026Article
- Association of albumin-corrected anion gap with all-cause and cardiovascular mortality in overactive bladder patients.Scientific reports · 2025Article
- Association between albumin-corrected anion gap and delirium in acute pancreatitis: insights from the MIMIC-IV database.BMC gastroenterology · 2025Article
- Prognostic value of albumin-corrected anion gap in critically ill patients with sepsis-associated liver injury: a retrospective study.BMC infectious diseases · 2025Article
- The association of albumin-corrected anion gap and acute kidney injury in heart failure patients: a competing risk model analysis.BMC cardiovascular disorders · 2025Article
- The Association Between Anion Gap and Albumin-Corrected Anion Gap with Sun Sensitivity: A National Retrospective Cross-Sectional Study.Clinical, cosmetic and investigational dermatology · 2025Article
- Article
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesLong-term uncontrolled hypertension increases the risk of kidney decompensation. This study aimed to explore the connection between albumin-corrected anion gap (ACAG) and kidney function in hypertensive patients.
methodsThis study utilized data from 1988 participants diagnosed with hypertension sourced from the NHANES database. Binary logistic regression analysis and subgroup analysis were utilized to investigate the relationship between ACAG and kidney function. The study employed restricted cubic spline (RCS) to assess the non-linear associations between ACAG and eGFR, as well as ACAG and ACR. Furthermore, mediation and moderation effect analyses were carried out, with blood pressure serving as the mediator and moderator, ACAG as the independent variable, and eGFR and ACR as the dependent variables. Finally, the study developed ACAG-based models for predicting kidney function decline.
resultsHigher ACAG is identified as an independent risk factor for eGFR < 60 mL/minute/1.73 m
conclusionsThe levels of ACAG are found to be independently associated with both eGFR and ACR. Additionally, ACAG shows promise as a new and dependable biomarker for predicting the decline in kidney function in hypertensive patients.
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