SynthesisJournal of periodontal research2025
Effectiveness of Implant Therapy in Patients With and Without a History of Periodontitis: A Systematic Review With Meta-Analysis of Prospective Cohort Studies.
Synthesis in Journal of periodontal research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Residual Periodontal Pockets at Implant Placement as Risk Indicator for Peri-Implantitis: A Systematic Review.Clinical implant dentistry and related research · 2026Pooled it
- Keratinized Mucosa Width and Incidence of Peri-Implant Diseases: A Systematic Review With Meta-Analysis.Journal of periodontal research · 2026Pooled it
- Tobacco Smoking and Smoke-Free Products as Risk Factors for Dental Implants: A Systematic Review.Clinical oral implants research · 2026Pooled it
- Non-surgical treatment of peri-implantitis with submarginal erythritol air-polishing in severe periodontitis patients: a randomized controlled trial.BMC oral health · 2026Trial
- Effect of Nonsurgical Mechanical Debridement With or Without Chlorhexidine Formulations in the Treatment of Peri-Implant Mucositis. A Randomized Placebo-Controlled Clinical Trial.Clinical oral implants research · 2025Trial
- Prior Tooth Mobility and Furcation Involvement Are Associated With Higher Dental Implant Failure Rates: A Propensity-Matched Cohort Study.Clinical oral implants research · 2026Article
- Peri-Implant Soft-Tissue Phenotype Modification for Refractory Peri-Implant Mucositis: A 12-Month Prospective Clinical Study With Ultrasonographic Analysis.Journal of periodontal research · 2026Observational
- Prevalence and Risk Indicators of Peri-Implant Diseases and Buccal Soft-Tissue Dehiscence: A Cross-Sectional Study From a University-Based Cohort.Journal of periodontal research · 2026Article
- The National Dental Practice-Based Research Network Dental Implant Restoration Registry to Evaluate Dental Implant Outcomes in Community Practice Settings: Protocol for a Prospective Observational Study.JMIR research protocols · 2026Observational
- Peri-Implantitis and Soft Tissue Dehiscence in a Turkish Population: Risk Indicators, Diagnostic Parameters and Biomarkers Discovery.Journal of periodontal research · 2026Article
- Incidence and Risk Factors of Peri-Implantitis Over Time-A Prospective Cohort Study.Journal of periodontal research · 2025Article
- Efficacy of adjunctive periodontal interventions in non-surgical periodontal therapy for Stage III/IV Grade C periodontitis: A systematic review and network meta-analysis.The Japanese dental science review · 2025Review
- Oral Microbiome Signatures in Periodontitis and Edentulism-A Population-Based Study.Journal of periodontal research · 2025Article
- Accuracy of Clinical Parameters in Predicting/Diagnosing Peri-Implant Bone Loss.Journal of clinical periodontology · 2025Article
- Outcomes of Dental Implants in Routine Clinical Practice: A Retrospective Multicenter Study.International journal of dentistry · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimThis systematic review investigates the effectiveness of implant therapy in patients with and without a history of periodontitis in terms of implant loss, peri-implant marginal bone loss (MBL), and occurrence of peri-implant diseases.
methodsThe protocol of the present meta-analysis was registered on PROSPERO (CRD42021264980). An electronic search was conducted up to April 2024. All prospective cohort studies reporting implant loss, MBL, and occurrence of peri-implant diseases in both patients with a history of periodontitis (HP) and patients with no history of periodontitis (NHP) after at least 36-month follow-up were included. The risk of bias was evaluated using the Newcastle-Ottawa Scale and the quality of the evidence was also assessed. A meta-analysis was performed on the selected outcomes at the available follow-up time points. Subgroup analyses were conducted based on follow-up time, rate of progression and severity of periodontitis, and implant surface characteristics. Publication bias was evaluated using the Funnel plot and Egger's test.
resultsFrom 13 761 initial records, 14 studies (17 articles) were finally included. Eight studies had a low risk of bias level, and six had a medium risk of bias level. Meta-analysis showed that HP patients had a significantly greater risk for implant loss (HR: 1.75; 95% CI: 1.28-2.40; p = 0.0005; I
conclusionsWithin the limits of heterogeneous case definitions and methods of assessment, a history of periodontitis has been proved to significantly increase the risk for implant loss, particularly at long follow-up (≥ 10 years) and in case of rapidly progressive forms (grade C), and for MBL and peri-implantitis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.