Evidence map›Paper›PMID 39466542›Full record

ArticleInsights into imaging2024

Comparison of image quality and lesion conspicuity between conventional and deep learning reconstruction in gadoxetic acid-enhanced liver MRI.

Jeong Hee Yoon, Jeong Eun Lee, So Hyun Park, Jin Young Park, Jae Hyun Kim, Jeong Min Lee

Registry-linked trialAbstract read
In one paragraph

Article in Insights into imaging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05182099 (AIRTM Deep Learning Reconstruction of Abdominal High Resolution Gd-EOB-DTPA Enhanced MRI in Patients With Suspicious Focal Liver Lesions), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05182099 naunknown statusnot on this map

AIRTM Deep Learning Reconstruction of Abdominal High Resolution Gd-EOB-DTPA Enhanced MRI in Patients With Suspicious Focal Liver Lesions: Image Quality Assessment

TypeinterventionalSponsorSeoul National University HospitalRan2022 to 2023Enrolled52ConditionsLiver Diseases, Magnetic Resonance Imaging, Deep LearningArmsLiver MRI
3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Accelerated Abdominal MRI: A Review of Current Methods and Applications.Journal of magnetic resonance imaging : JMRI · 2025
    Review
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  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jeong Hee YoonDepartment of Radiology, Seoul National University Hospital and College of Medicine, Seoul, Republic of Korea.
Jeong Eun LeeDepartment of Radiology, Chungnam National University Hospital and College of Medicine, Daejeon, Republic of Korea.
So Hyun ParkDepartment of Radiology, Gachon University Gil Medical Center, Incheon, Republic of Korea.
Jin Young ParkDepartment of Radiology, Inje University Busan Paik Hospital, Busan, Republic of Korea.
Jae Hyun KimDepartment of Radiology, Seoul National University Hospital and College of Medicine, Seoul, Republic of Korea.
Jeong Min LeeDepartment of Radiology, Seoul National University Hospital and College of Medicine, Seoul, Republic of Korea. jmsh@snu.ac.kr.ORCID http://orcid.org/0000-0003-0561-8777

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo compare the image quality and lesion conspicuity of conventional vs deep learning (DL)-based reconstructed three-dimensional T1-weighted images in gadoxetic acid-enhanced liver magnetic resonance imaging (MRI).

methodsThis prospective study (NCT05182099) enrolled participants scheduled for gadoxetic acid-enhanced liver MRI due to suspected focal liver lesions (FLLs) who provided signed informed consent. A liver MRI was conducted using a 3-T scanner. T1-weighted images were reconstructed using both conventional and DL-based (AIR

resultsFifty participants (male = 36, mean age 62 ± 11 years) were included for image analysis. The DL-based reconstruction showed significantly higher image quality than conventional images in all phases (3.71-4.40 vs 3.37-3.99, p < 0.001 for all), as well as significantly less noise and ringing artifacts than conventional images (p < 0.05 for all), while also showing significantly altered image texture (p < 0.001 for all). Lesion conspicuity was significantly higher in DL-reconstructed images than in conventional images in the arterial phase (2.15 [95% confidence interval: 1.78, 2.52] vs 2.03 [1.65, 2.40], p = 0.036), but no significant difference was observed in the portal venous phase and hepatobiliary phase (p > 0.05 for all). There was no significant difference in the figure-of-merit (0.728 in DL vs 0.709 in conventional image, p = 0.474).

conclusionDL reconstruction provided higher-quality three-dimensional T1-weighted imaging than conventional reconstruction in gadoxetic acid-enhanced liver MRI. CRITICAL RELEVANCE STATEMENT: DL reconstruction of 3D T1-weighted images improves image quality and arterial phase lesion conspicuity in gadoxetic acid-enhanced liver MRI compared to conventional reconstruction. KEY POINTS: DL reconstruction is feasible for 3D T1-weighted images across different spatial resolutions and phases. DL reconstruction showed superior image quality with reduced noise and ringing artifacts. Hepatic anatomic structures were more conspicuous on DL-reconstructed images.

Indexed as

Deep learningImage enhancementLiverMagnetic resonance imaging

Identifiers

PMID39466542
PMCPMC11519238

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.