Evidence map›Paper›PMID 39466500›Full record

ArticleOral and maxillofacial surgery2024

Soft-tissue keratocyst: report of 3 new cases from Brazil.

Thayanne Oliveira de Freitas Gonçalves, Ana Karolina Daquer, Luana D'arc Diafilos Teixeira, Thamiris Castro Abrantes, Oswaldo Belloti, Alexandre Maurity, Victor Luiz Cunha Dos Santos, Nathalia Schettini Setubal Ferme, Michelle Agostini, Ana Luiza Oliveira Corrêa Roza and 2 more

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Article in Oral and maxillofacial surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

12 authors.

Thayanne Oliveira de Freitas GonçalvesDepartment of Oral Diagnosis and Pathology, School of Dentistry, Federal University of Rio de Janeiro (UFRJ), Av. Carlos Chagas Filho 373, Prédio do CCS Bloco K, 2° andar Sala 56. Ilha da Cidade Universitária 21.941-902, Rio de Janeiro, Brazil.
Ana Karolina DaquerDepartment of Oral Diagnosis and Pathology, School of Dentistry, Federal University of Rio de Janeiro (UFRJ), Av. Carlos Chagas Filho 373, Prédio do CCS Bloco K, 2° andar Sala 56. Ilha da Cidade Universitária 21.941-902, Rio de Janeiro, Brazil.
Luana D'arc Diafilos TeixeiraDepartment of Oral Diagnosis and Pathology, School of Dentistry, Federal University of Rio de Janeiro (UFRJ), Av. Carlos Chagas Filho 373, Prédio do CCS Bloco K, 2° andar Sala 56. Ilha da Cidade Universitária 21.941-902, Rio de Janeiro, Brazil.
Thamiris Castro AbrantesDepartment of Oral Diagnosis and Pathology, School of Dentistry, Federal University of Rio de Janeiro (UFRJ), Av. Carlos Chagas Filho 373, Prédio do CCS Bloco K, 2° andar Sala 56. Ilha da Cidade Universitária 21.941-902, Rio de Janeiro, Brazil.
Oswaldo BellotiOral Medicine Service, Prefeitura de Santo Antonio de Padua, Rio de Janeiro, Brazil.
Alexandre MaurityOral and Maxillofacial Surgery Residency Program, Hospital Federal de Bonsucesso, Rio de Janeiro, Brazil.
Victor Luiz Cunha Dos SantosOral and Maxillofacial Surgery Residency Program, Hospital Federal de Bonsucesso, Rio de Janeiro, Brazil.
Nathalia Schettini Setubal FermeOral and Maxillofacial Surgery Residency Program, Hospital Universitário Clementino Fraga Filho, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, Brazil.
Michelle AgostiniDepartment of Oral Diagnosis and Pathology, School of Dentistry, Federal University of Rio de Janeiro (UFRJ), Av. Carlos Chagas Filho 373, Prédio do CCS Bloco K, 2° andar Sala 56. Ilha da Cidade Universitária 21.941-902, Rio de Janeiro, Brazil.
Ana Luiza Oliveira Corrêa RozaDepartment of Oral Diagnosis, Piracicaba Dental School, University of Campinas (UNICAMP), Piracicaba, Brazil.
Aline Corrêa AbrahãoDepartment of Oral Diagnosis and Pathology, School of Dentistry, Federal University of Rio de Janeiro (UFRJ), Av. Carlos Chagas Filho 373, Prédio do CCS Bloco K, 2° andar Sala 56. Ilha da Cidade Universitária 21.941-902, Rio de Janeiro, Brazil.
Mário José RomañachDepartment of Oral Diagnosis and Pathology, School of Dentistry, Federal University of Rio de Janeiro (UFRJ), Av. Carlos Chagas Filho 373, Prédio do CCS Bloco K, 2° andar Sala 56. Ilha da Cidade Universitária 21.941-902, Rio de Janeiro, Brazil. marioromanach@ufrj.br.

Funding

Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro E-26/201.340/2022 [272477]Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro E-26/201.383/2022 [272817]
6 · The paper itself

Abstract

objectiveTo describe the clinicopathological features of 3 new cases of soft-tissue keratocyst (STK) of the buccal mucosa from Brazil. MATERIALS AND

methodsClinical data from 3 patients diagnosed with STK were obtained from the archives of the Laboratory of Oral Pathology at the Federal University of Rio de Janeiro- Brazil from 2020 to 2023. Two oral pathologists reviewed conventional hematoxylin and eosin-stained slides of each case. Immunohistochemical stainings for CK19, Bcl-2, CD138, D2-40, EMA, and Ki-67 were performed in all cases.

resultsCase 1 was a 58-year-old man with a 2-year history of painless swelling of the right buccal mucosa, measuring approximately 5 cm. Case 2 was of a 44-year-old man with a painful swelling in the left buccal mucosa lasting 3 years with drainage to the oral cavity. Case 3 was of a 74-year-old woman with a painful swelling in the left buccal mucosa of unknown duration. Microscopic evaluation of all 3 cases revealed a cyst lined with a few cell layers composed of columnar palisading basal cells and a corrugated parakeratin surface. The capsule comprised fibrous connective tissue with variable amounts of blood vessels with hemorrhage, nerve bundles, fat tissue, striated muscle fibers, and the absence of pilosebaceous units. No recurrence was observed after complete surgical removal. All epithelial layers of the 3 cases expressed positivity for CK19 and CD138, the basal cells were positive for Bcl-2 and D2-40, and the superficial epithelial layer was positive for EMA. All cases demonstrated a low proliferation index by Ki-67.

conclusionThis study represents a series of 3 cases of STK that affected the posterior buccal mucosa of middle-aged patients from Brazil, sharing histopathological and immunohistochemical features with odontogenic keratocyst.

Indexed as

Mouth MucosaAdultAgedBrazilCystsFemaleHumansMaleMiddle AgedMouth DiseasesBuccal mucosaOdontogenic keratocystSoft-tissue keratocystSteatocystoma

Identifiers

PMID39466500

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