Evidence map›Paper›PMID 39466457›Full record

ArticleWorld journal of urology2024

Effect of intrarenal pelvic pressure on pyelo-tubular backflow and renal cortical blood perfusion during mini-percutaneous nephrolithotomy.

Lei Zhou, Chen Zhang, Xiao-Lin Zhan, Mian Li, Nan-Yan Luo, Wei-Wei Wu, Xiao-Ma Zhang

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Article in World journal of urology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

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4citing papers in PubMed
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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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3 · Its place in the literature

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4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Lei ZhouDepartment of Urology, Anhui Public Health Clinical Center, The First Affiliated Hospital of Anhui Medical University, Hefei, 230012, China.
Chen ZhangDepartment of Urology, Anhui Public Health Clinical Center, The First Affiliated Hospital of Anhui Medical University, Hefei, 230012, China.
Xiao-Lin ZhanDepartment of Ultrasonography, Anhui Public Health Clinical Center, The First Affiliated Hospital of Anhui Medical University, Hefei, 230012, China.
Mian LiDepartment of Ultrasonography, Anhui Public Health Clinical Center, The First Affiliated Hospital of Anhui Medical University, Hefei, 230012, China.
Nan-Yan LuoDepartment of Ultrasonography, Anhui Public Health Clinical Center, The First Affiliated Hospital of Anhui Medical University, Hefei, 230012, China.
Wei-Wei WuDepartment of Anesthesiology, Anhui Public Health Clinical Center, The First Affiliated Hospital of Anhui Medical University, Hefei, 230012, China.
Xiao-Ma ZhangDepartment of Urology, Anhui Public Health Clinical Center, The First Affiliated Hospital of Anhui Medical University, Hefei, 230012, China. zhangxiaoma8@126.com.ORCID http://orcid.org/0000-0001-7138-7909

Funding

the Hospital Research and Cultivation Foundation 2022YKJ13
6 · The paper itself

Abstract

purposeTo investigate the effects of intrarenal pelvic pressure (IPP) on pyelo-tubular backflow and renal cortical blood perfusion during mini-percutaneous nephrolithotomy (MPCNL).

methodsDynamic changes in pyelo-tubular backflow and renal cortical blood perfusion were studied in six patients undergoing MPCNL using dynamic contrast-enhanced ultrasonography (CEUS) and IPP monitoring.

resultsCEUS of intrarenal pelvic perfusion revealed that renal tubules began to exhibit contrast agent reflux when IPP exceeded 34 mmHg during the MPCNL procedure. There was a positive correlation between renal tubule contrast agent reflux and IPP (P < 0.05). Intravenous CEUS of renal cortical blood flow demonstrated that both intrarenal pelvic perfusion time and IPP during MPCNL significantly affected renal cortical blood perfusion. Intrarenal pelvic perfusion time and pressure were negatively correlated with contrast agent peak intensity (PI) and area under the curve (AUC) (P < 0.05). Longer intrarenal pelvic perfusion times and higher pressures resulted in decreased renal cortical blood perfusion.

conclusionThis study directly confirmed through dynamic CEUS and real-time IPP monitoring that an increase in IPP above the threshold of approximately 34 mmHg during MPCNL in patients leads to reflux through the renal tubules and a significant decrease in renal cortical blood perfusion. The safe upper limit for intrarenal pelvic perfusion pressure during MPCNL is approximately 34 mmHg.

Indexed as

Kidney CortexKidney PelvisNephrolithotomy, PercutaneousRenal CirculationUltrasonographyAdultContrast MediaFemaleHumansKidney CalculiMaleMiddle AgedPressureContrast MediaContrast-enhanced ultrasoundIntrarenal pelvic pressurePercutaneous nephrolithotomyPyelo-tubular backflowRenal cortical blood perfusion

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.