Evidence map›Paper›PMID 39466446›Full record

ArticleSocial psychiatry and psychiatric epidemiology2025

The annual trend of suicide rates from 2010 to 2021 in patients with cannabis use disorder - a national registry study.

Martin Ø Myhre, Eline Borger Rognli, Fredrik A Walby, Jørgen G Bramness, Lars Mehlum

Abstract read
In one paragraph

Article in Social psychiatry and psychiatric epidemiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Martin Ø MyhreInstitute for Clinical Medicine, National Centre for Suicide Research and Prevention, University of Oslo, Oslo, Norway. m.o.myhre@medisin.uio.no.ORCID http://orcid.org/0000-0002-9349-8922
Eline Borger RognliSection for Clinical Addiction Research, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.ORCID http://orcid.org/0000-0002-7248-3019
Fredrik A WalbyInstitute for Clinical Medicine, National Centre for Suicide Research and Prevention, University of Oslo, Oslo, Norway.ORCID http://orcid.org/0000-0001-5154-7397
Jørgen G BramnessSection for Clinical Addiction Research, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.ORCID http://orcid.org/0000-0002-9250-3144
Lars MehlumInstitute for Clinical Medicine, National Centre for Suicide Research and Prevention, University of Oslo, Oslo, Norway.ORCID http://orcid.org/0000-0003-2813-0045

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe temporal trend of suicide in patients with cannabis use disorder (CUD) is important to investigate, considering the recent increases in THC concentration in cannabis products. This study describes the annual suicide rates in patients with CUD from 2010 to 2021. To investigate if any change in suicide rate was specific to CUD, we compared these suicide rates with corresponding data for patients with alcohol use disorders (AUD) and other substance use disorders (SUDs).

methodThe study used a time series design. We used a national registry linkage between the Norwegian Cause of Death Registry and the Norwegian Patient Registry from 2010 to 2021, including patients with CUD (ICD-10 code F12), AUD (F10), or other SUDs (F11; F13-F16; F18-F19) who died by suicide, supplemented with the total number of patients treated with specific disorders to estimate the suicide rates. The trend was analyzed by comparing the annual suicide rate to 2010 and using Poisson regression, adjusting for gender, age, and mental disorders.

resultsWe found increased annual incidence rate ratios for patients with CUD in 2018 (IRR = 2.14 (95% CI 1.14-3.99)) and onwards and an increasing time trend over the study period (IRR = 1.08 (1.05-1.12)). No increases in trends were found for AUD or other SUDs. The time trend for CUD was attenuated when adjusting for depressive or anxiety disorders (aIRR = 1.00 (0.92-1.08)) or other SUDs (aIRR = 0.96 (0.87-1.06)).

conclusionsIncreasing suicide rates were found in patients with CUD. Comorbid anxiety and depression or other SUDs, but not other mental disorders, could partly explain these results.

Indexed as

Marijuana AbuseSuicideAdolescentAdultAgedCause of DeathFemaleHumansIncidenceMaleMiddle AgedNorwayRegistriesYoung AdultAlcohol use disordersCannabis use disordersSubstance use disordersSuicideTime series

Identifiers

PMID39466446
PMCPMC12238203

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.