Evidence map›Paper›PMID 39465483›Full record

ArticleJournal of fluorescence2025

A Novel Carbon Dot-Bromothymol Blue System for Ratiometric Colorimetric-Fluorometric Sensing of Glutathione in Urine: A Smartphone-Compatible Approach.

Ahmed Z Alanazi, Khalid Alhazzani, Aya M Mostafa, James Barker, Hossieny Ibrahim, Mohamed M El-Wekil, Al-Montaser Bellah H Ali

Abstract read
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Article in Journal of fluorescence, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ahmed Z AlanaziDepartment of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Khalid AlhazzaniDepartment of Pharmacology and Toxicology, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
Aya M MostafaSchool of Life Sciences, Pharmacy, and Chemistry, Kingston University, Kingston-Upon-Thames, London, KT1 2EE, UK.
James BarkerSchool of Life Sciences, Pharmacy, and Chemistry, Kingston University, Kingston-Upon-Thames, London, KT1 2EE, UK.
Hossieny IbrahimDepartment of Chemistry, Faculty of Science, Assiut University, Assiut, 71516, Egypt.
Mohamed M El-WekilDepartment of Pharmaceutical Analytical Chemistry, Faculty of Pharmacy, Assiut University, Assiut, Egypt.
Al-Montaser Bellah H AliDepartment of Pharmaceutical Analytical Chemistry, Faculty of Pharmacy, Assiut University, Assiut, Egypt. Almontaser_bellah@aun.edu.eg.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study presents a novel dual-modal approach for glutathione (GSH) detection using blue and yellow dual-emission carbon dots (BY-CDs) and bromothymol blue (BTB) at pH 8.0. The method employs both colorimetric and fluorometric detection modes, offering a new perspective on GSH quantification. BTB's blue coloration induces selective fluorescence quenching of the CDs' 610 nm emission peak, with minimal effect on the 445 nm peak. Upon GSH addition, the quinonoid structure (blue color) of BTB transforms to its benzenoid form (yellow color). This transformation triggers fluorescence restoration at 610 nm and significant quenching at 445 nm, enabling ratiometric fluorescence analysis (F

Indexed as

Bromthymol BlueCarbonColorimetryFluorescent DyesFluorometryGlutathioneQuantum DotsSmartphoneHumansSpectrometry, FluorescenceBromthymol BlueCarbonFluorescent DyesGlutathioneDual-detectionDual-emission carbon dotsGlutathioneSmartphone-based platformThymol blue

Identifiers

PMID39465483

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.