Evidence map›Paper›PMID 39465359›Full record

ArticleLipids in health and disease2024

The effect of blood lipids on the comorbidity of multiple large arachnoid granulations.

Yibing Guo, Zhongao Wang, Meini Gao, Da Zhou, Yuchuan Ding, Xunming Ji, Ran Meng

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Lipids in health and disease, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Yibing Guo *Department of Neurology, Xuanwu Hospital, Capital Medical University, National Center for Neurological Disorders, Beijing, 100053, China.
Zhongao Wang *Department of Neurology, Xuanwu Hospital, Capital Medical University, National Center for Neurological Disorders, Beijing, 100053, China.ORCID http://orcid.org/0000-0002-4234-7593
Meini GaoDepartment of Neurology, Xuanwu Hospital, Capital Medical University, National Center for Neurological Disorders, Beijing, 100053, China.
Da ZhouDepartment of Neurology, Xuanwu Hospital, Capital Medical University, National Center for Neurological Disorders, Beijing, 100053, China.
Yuchuan DingDepartment of Neurosurgery, Wayne State University School of Medicine, Detroit, MI, 48201, USA.
Xunming JiDepartment of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, 100053, China.ORCID http://orcid.org/0000-0003-0293-2744
Ran MengDepartment of Neurology, Xuanwu Hospital, Capital Medical University, National Center for Neurological Disorders, Beijing, 100053, China. victor65@126.com.ORCID http://orcid.org/0000-0003-1190-4710

Funding

National Natural Science Foundation of China 82171297, 82101390Natural Science Foundation of Beijing Municipality 7212047
6 · The paper itself

Abstract

backgroundCurrently, studies on the formation mechanism for the enlargement of arachnoid granulation (AG) are lacking. The impact of dyslipidemia on the formation of multiple large arachnoid granulations (LAGs) was studied in this research.

methodsThe study included patients diagnosed with cerebral venous sinus stenosis (CVSS) related to LAG. The number of LAGs was assessed via high-resolution black blood magnetic resonance imaging. The relationships between blood lipids and multiple LAGs were explored to evaluate the effects of dyslipidemia on the formation of multiple LAGs.

resultsA total of 163 participants with a diagnosis of LAG were included. The levels of total cholesterol (TC) (P = 0.004) and low-density lipoprotein cholesterol (LDL-c) (P = 0.01) in the multiple LAGs group were greater than those in the non-multiple LAGs group. Multivariate logistic regression analysis revealed that TC (odds ratio (OR), 2.19; 95% confidence interval (CI), 1.26-3.80; P = 0.006) and LDL-c (OR, 2.18; 95% CI, 1.16-4.07; P = 0.02) were independently associated with multiple LAGs.

conclusionsTC and LDL-c are independently related to multiple LAGs, indicating that dyslipidemia may be a potential cause of CVSS. Therefore, monitoring blood lipids may be necessary for patients with LAGs.

Indexed as

ArachnoidCholesterol, LDLDyslipidemiasAdultAgedCholesterolComorbidityFemaleHumansLipidsMagnetic Resonance ImagingMaleMiddle AgedCholesterolCholesterol, LDLLipidsArachnoid granulationBlood lipidCerebral venous sinus stenosisDyslipidemiaHigh-resolution black blood magnetic resonance imaging

Identifiers

PMID39465359
PMCPMC11514773

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