Evidence map›Paper›PMID 39464884›Full record

ArticleFrontiers in immunology2024

Clinical associations of complement-activating collectins, collectin-10, collectin-11 and mannose-binding lectin in preterm neonates.

Gabriela Gajek, Soren W K Hansen, Dariusz Jarych, Maja Kufelnicka-Babout, Anna S Świerzko, Paulina Kobiela, Agnieszka Szala-Poździej, Karolina Chojnacka, Katarzyna Sobczuk, Iwona Domżalska-Popadiuk and 4 more

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Article in Frontiers in immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Gabriela GajekLaboratory of Immunobiology of Infections, Institute of Medical Biology, Polish Academy of Sciences, Łódź, Poland.
Soren W K HansenDepartment of Cancer and Inflammation Research, Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark.
Dariusz JarychLaboratory of Immunobiology of Infections, Institute of Medical Biology, Polish Academy of Sciences, Łódź, Poland.
Maja Kufelnicka-BaboutDepartment of Perinatology, First Chair of Gynecology and Obstetrics, Medical University of Łódź, Łódź, Poland.
Anna S ŚwierzkoLaboratory of Immunobiology of Infections, Institute of Medical Biology, Polish Academy of Sciences, Łódź, Poland.
Paulina KobielaDepartment of Neonatology, Medical University of Gdańsk, Gdańsk, Poland.
Agnieszka Szala-PoździejLaboratory of Immunobiology of Infections, Institute of Medical Biology, Polish Academy of Sciences, Łódź, Poland.
Karolina ChojnackaII Department of Neonatology, Poznań University of Medical Sciences, Poznań, Poland.
Katarzyna SobczukDepartment of Perinatology, First Chair of Gynecology and Obstetrics, Medical University of Łódź, Łódź, Poland.
Iwona Domżalska-PopadiukDepartment of Neonatology, Medical University of Gdańsk, Gdańsk, Poland.
Jan MazelaDepartment of Neonatology, Poznań University of Medical Sciences, Poznań, Poland.
Jarosław KalinkaDepartment of Perinatology, First Chair of Gynecology and Obstetrics, Medical University of Łódź, Łódź, Poland.
Steffen ThielDepartment of Biomedicine, Aarhus University, Aarhus, Denmark.
Maciej CedzyńskiLaboratory of Immunobiology of Infections, Institute of Medical Biology, Polish Academy of Sciences, Łódź, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Premature and low-birthweight infants are at especially high risk of perinatal complications, including impaired thermoregulation, infections and respiratory distress. Such adverse effects and the need for invasive procedures are associated with high mortality among preterms. This study focused on the influence of the innate immune system and tested the levels of collectins, collectin-10 (CL-10), collectin-11 (CL-11) and mannose-binding lectin (MBL) in preterm neonates. Methods: Cord blood was collected from 535 preterms (born at gestational age ≤37 weeks). Findings: Low concentrations of CL-10 in cord sera (<462 ng/ml corresponding to the 10 Conclusion: The complement-activating collectins investigated here could be important for maintaining homeostasis in preterm neonates. Despite similar structure and specificity, MBL, CL-10 and CL-11 manifest a different spectrum of clinical associations.

Indexed as

CollectinsInfant, PrematureMannose-Binding LectinComplement ActivationFemaleFetal BloodGestational AgeHumansInfant, NewbornMalePolymorphism, Single NucleotideCOLEC10 protein, humanColec11 protein, humanCollectinsMannose-Binding LectinMBL2 protein, humanCL-10CL-11collectincomplementmannose-binding lectin (MBL)neonateprematurityrespiratory distress syndrome (RDS)

Identifiers

PMID39464884
PMCPMC11502412

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.