Evidence map›Paper›PMID 39464858›Full record

ArticleJAC-antimicrobial resistance2024

Real-world performance of susceptibility testing for cefiderocol: insights from a prospective multicentre study on Gram-negative bacteria.

Alvaro Irigoyen-von-Sierakowski, Azahara Ocaña, Rosa Sánchez-Mayoral, Emilia Cercenado, GEIRAS-SEIMC Study Group

Abstract read
In one paragraph

Article in JAC-antimicrobial resistance, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. Antibiotics (Basel, Switzerland) · 2026
    Article
  4. Update on the comparativeJAC-antimicrobial resistance · 2026
    Article
  5. Review
  6. Article
  7. Review
  8. Genetic characterization of carbapenem-resistantFrontiers in cellular and infection microbiology · 2026
    Article
  9. Siderophore cephalosporins.EcoSal Plus · 2025
    Review
  10. Article
  11. Microbiology spectrum · 2025
    Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Alvaro Irigoyen-von-SierakowskiDepartment of Clinical Microbiology and Infectious Diseases, Gregorio Marañón General University Hospital, Dr. Esquerdo 46, Madrid 28007, Spain.ORCID https://orcid.org/0000-0002-5137-8818
Azahara OcañaDepartment of Clinical Microbiology and Infectious Diseases, Gregorio Marañón General University Hospital, Dr. Esquerdo 46, Madrid 28007, Spain.
Rosa Sánchez-MayoralDepartment of Clinical Microbiology and Infectious Diseases, Gregorio Marañón General University Hospital, Dr. Esquerdo 46, Madrid 28007, Spain.
Emilia CercenadoDepartment of Clinical Microbiology and Infectious Diseases, Gregorio Marañón General University Hospital, Dr. Esquerdo 46, Madrid 28007, Spain.ORCID https://orcid.org/0000-0002-5279-3773
GEIRAS-SEIMC Study Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Cefiderocol is a novel siderophore-conjugated cephalosporin developed for the treatment of multidrug-resistant Gram-negative bacterial (GNB) infections. However, the current gold standard for cefiderocol susceptibility testing, broth microdilution (BMD) using iron-depleted cation-adjusted Mueller-Hinton broth, presents challenges for many microbiology laboratories. In this study, we evaluate the real-world performance of disc diffusion (DD) and a commercial BMD method (ComASP Methods: The susceptibilities of 1472 isolates (632 Enterobacterales, 532 Results: A total of 1408 and 1450 isolates were susceptible by DD and ComASP Conclusions: DD is a straightforward, rapid and accessible method for routine determination of cefiderocol susceptibility in real-world practice. ComASP

Identifiers

PMID39464858
PMCPMC11503648

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.