Evidence map›Paper›PMID 39464767›Full record

ArticleRomanian journal of ophthalmology

Floppy iris. How is floppy iris syndrome managed? What do urologists and ophthalmologists say?

Bogdan Bumbuluț, Dan Mircea Stănilă

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Article in Romanian journal of ophthalmology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

2 authors.

Bogdan BumbuluțSibiu County Emergency Clinical Hospital, Sibiu, Romania.
Dan Mircea StănilăDr. Stănilă Medical Centre, Ofta Total Clinic, "Lucian Blaga" University of Sibiu, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: This study focuses on the effect of chronic treatment on the eye, regarding the so-called Intraoperative Floppy Iris Syndrome (IFIS) or Floppy Iris Syndrome, which can occur during cataract surgery. Aim: The study aimed to establish the influence of tamsulosin, used in benign prostatic hyperplasia (BPH) treatment on the iris, during cataract surgery, considering the increased incidence of both conditions in older age. Methods: This study included one hundred male patients, operated on for cataracts at the Ofta Total Clinic and Dr. Stănilă Medical Centre, in Sibiu, out of 601 patients operated on for cataracts between February and October 2022. Of the 100 patients, 24 used medication for BPH. 5 patients used prostamol, a phytotherapeutic preparation, which is an extract from Serenoarepens, and the remaining 19 used tamsulosin, which is an alpha-blocker, most commonly used in the treatment of BPH, considered the first-line treatment option. Results: In 15 patients, we intraoperatively managed, a medium mydriasis through pharmacological dilation, including intracameral administration of phenocaine and mechanical dilation or stripping. In 4 patients it was necessary to apply iris dilators. Due to the small pupil in 2 patients, we caught the iris in the phacoemulsification probe, and a small, incomplete iris coloboma was formed. Sometimes, there was a turnover of Descemet in 4 patients. The pupil remained semi-dilated and slightly areflective in the patients to whom we applied iris hooks. The patients' visual acuity was satisfactory, between 0.9 and 0.6. Discussions: The topic gives rise to many discussions. It seems that stopping the administration of tamsulosin for a short time does not help the occurrence of IFIS, because the iris lesions seem irreversible. Patients at risk of developing cataracts should be evaluated and possibly referred to an ophthalmologist to determine surgery before starting treatment for BPH and to competently assess the administration of this medication. Conclusions: Collaboration between urologists and ophthalmologists is required for patients prone to the appearance of cataracts since both conditions are frequently encountered in elderly patients.

Indexed as

Cataract ExtractionIris DiseasesProstatic HyperplasiaTamsulosinAdrenergic alpha-1 Receptor AntagonistsAgedAged, 80 and overHumansIntraoperative ComplicationsIrisMaleMiddle AgedOphthalmologistsRetrospective StudiesSyndromeUrologistsAdrenergic alpha-1 Receptor AntagonistsTamsulosinbenign prostatic hypertrophyBPH = Benign Prostatic HyperplasiaFloppy irisIFIS = Intraoperative Floppy Iris SyndromeNSAIDs = Non-Steroidal Anti-Inflammatory Drugstamsulosin

Identifiers

PMID39464767
PMCPMC11503239

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.