Evidence map›Paper›PMID 39464744›Full record

ArticlemicroLife2024

Acetylomics reveals an extensive acetylation diversity within

Nand Broeckaert, Hannelore Longin, Hanne Hendrix, Jeroen De Smet, Mirita Franz-Wachtel, Boris Maček, Vera van Noort, Rob Lavigne

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in microLife, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Nand BroeckaertComputational Systems Biology, Department of Microbial and Molecular Systems, KU Leuven, Kasteelpark Arenberg 20 box 2460, 3001 Heverlee, Belgium.ORCID https://orcid.org/0000-0001-6823-5875
Hannelore LonginComputational Systems Biology, Department of Microbial and Molecular Systems, KU Leuven, Kasteelpark Arenberg 20 box 2460, 3001 Heverlee, Belgium.ORCID https://orcid.org/0000-0001-8524-5768
Hanne HendrixLaboratory of Gene Technology, Department of Biosystems, KU Leuven, Kasteelpark Arenberg 21 box 2462, 3001 Heverlee, Belgium.
Jeroen De SmetResearch Group for Insect Production and Processing, Department of Microbial and Molecular Systems (M²S), KU Leuven, Kleinhoefstraat 4, 2440 Geel, Belgium.
Mirita Franz-WachtelProteome Center Tuebingen, Institute of Cell Biology, University of Tübingen, Auf d. Morgenstelle 15, D-72076 Tübingen, Germany.
Boris MačekProteome Center Tuebingen, Institute of Cell Biology, University of Tübingen, Auf d. Morgenstelle 15, D-72076 Tübingen, Germany.
Vera van NoortComputational Systems Biology, Department of Microbial and Molecular Systems, KU Leuven, Kasteelpark Arenberg 20 box 2460, 3001 Heverlee, Belgium.ORCID https://orcid.org/0000-0002-8436-6602
Rob LavigneLaboratory of Gene Technology, Department of Biosystems, KU Leuven, Kasteelpark Arenberg 21 box 2462, 3001 Heverlee, Belgium.ORCID https://orcid.org/0000-0001-7377-1314

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacteria employ a myriad of regulatory mechanisms to adapt to the continuously changing environments that they face. They can, for example, use post-translational modifications, such as Nε-lysine acetylation, to alter enzyme activity. Although a lot of progress has been made, the extent and role of lysine acetylation in many bacterial strains remains uncharted. Here, we applied stable isotope labeling by amino acids in cell culture (SILAC) in combination with the immunoprecipitation of acetylated peptides and LC-MS/MS to measure the first

Indexed as

acetylomeinterstrain analysisNε-lysine acetylationPA14PAO1Pseudomonas aeruginosa

Identifiers

PMID39464744
PMCPMC11512479

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.