Evidence map›Paper›PMID 39464266›Full record

ArticleGlobal bioethics enquiry2023

Stakeholder views on future use of biological samples in Malawi and South Africa.

Francis Masiye, Walter Jaoko, Stuart Rennie

Abstract read
In one paragraph

Article in Global bioethics enquiry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Francis MasiyeMalawi University of Science and Technology, Ndata Farm, Thyolo, Malawi.
Walter JaokoStellenbosch University, Centre for Medical Ethics and Law, Cape Town, South Africa.
Stuart RennieUniversity of Nairobi, Nairobi, Kenya.

Funding

Advancing Research Ethics Training in Southern Africa (ARESA): Leadership ProgramD43TW010511 · FIC · STELLENBOSCH UNIVERSITY · PI MOODLEY, KEYMANTHRI, RENNIE, STUART · 2017 to 2021
$1.2M
Community Engagement for H3Africa Biobanking Research: The Tygerberg ModelU01HG008222 · NHGRI · STELLENBOSCH UNIVERSITY · PI MOODLEY, KEYMANTHRI · 2015 to 2017
$205k
FIC NIH HHS D43 TW010511NHGRI NIH HHS U01 HG008222
6 · The paper itself

Abstract

Background: Current advances in biomedical research have introduced new ethical challenges regarding the storage and future use of biological samples in low- and middle-income settings. Few studies have explored key stakeholder views on storage and future use of biological samples in sub-Saharan Africa. Therefore, an empirical study was conducted to understand key stakeholder views on storage and future use of biological samples in Malawi and South Africa. The main objective was to explore key stakeholder views on current policies on storage and future use of biological samples and use the information obtained to advise on policy implications for future use of biological samples in Malawi and South Africa. Methodology: This was a qualitative study involving in-depth interviews and focus group discussions. Seventy-eight participants were recruited in both countries and took part in 34 IDIs and 6 FGDs. Audio-recordings were transcribed verbatim, and data analyzed thematically, iteratively and inductively using ATLAS. The study was conducted in Cape Town, South Africa, and Blantyre and Lilongwe in Malawi. Results: Most participants recommended future use of biological samples and their indefinite storage. Majority of the participants felt donors of biological samples are the rightful owners of the samples. Few participants recommended that biological samples for a specific study must be destroyed at the end of the study. Conclusion: These findings may inform ongoing ethical debates on storage and future use of biological samples. They may also inform policy changes in Malawi and South Africa on the length of storage of biological samples.

Indexed as

Biological samplesdestruction of samplesfocus group discussion and in-depth interviewindefinite storage

Identifiers

PMID39464266
PMCPMC11511626

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.