Evidence map›Paper›PMID 39464260›Full record

ArticleClinical kidney journal2024

Design and cohort characteristics of TRACK, a prospective study of hyperkalaemia management decision-making.

Judith Hsia, Nitin Shivappa, Ameet Bakhai, Jordi Bover, Javed Butler, Pietro Manuel Ferraro, Linda Fried, Markus P Schneider, Navdeep Tangri, Wolfgang C Winkelmayer and 4 more

Registry-linked trialAbstract read
In one paragraph

Article in Clinical kidney journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05408039 (A Prospective, Non-interventional, Longitudinal Study of the Treatment Journey of Adult Patients With Hyperkalemia), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05408039 completednot on this map

A Prospective, Non-interventional, Longitudinal Study of the Treatment Journey of Adult Patients With Hyperkalemia

TypeobservationalSponsorAstraZenecaRan2022 to 2024Enrolled1,331ConditionsHyperkalemia
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Judith HsiaCPC Clinical Research, University of Colorado, Aurora, CO, USA.ORCID https://orcid.org/0000-0002-3413-7836
Nitin ShivappaAstraZeneca, Wilmington, DE, USA.
Ameet BakhaiRoyal Free NHS Hospital, London, UK.
Jordi BoverHospital Germans Trias i Pujol, Badalona, Spain.
Javed ButlerBaylor Scott & White Research Institute, Dallas, TX, and University of Mississippi, Jackson, MI, USA.ORCID https://orcid.org/0000-0001-7683-4720
Pietro Manuel FerraroUniversità degli Studi di Verona, Verona, Italy.ORCID https://orcid.org/0000-0002-1379-022X
Linda FriedPittsburgh Healthcare System, Pittsburgh, PA, USA.
Markus P SchneiderUniversity of Erlangen-Nürnberg, Erlangen, Germany.
Navdeep TangriUniversity of Manitoba, Winnipeg, MB, Canada.
Wolfgang C WinkelmayerBaylor College of Medicine, Houston, TX, USA.
Meredith BishopAstraZeneca, Gaithersburg, MD, USA.
Hungta ChenAstraZeneca, Wilmington, DE, USA.
Anna-Karin SundinAstraZeneca, Gothenburg, Sweden.
Marc P BonacaCPC Clinical Research, University of Colorado, Aurora, CO, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Guideline-recommended hyperkalaemia management includes dietary potassium (K Methods: This study enrolled participants within 21 days of an episode of hyperkalaemia in four European countries (UK, Spain, Germany, Italy) and the USA. During the 12-month follow up, data collected will include participant and healthcare provider characteristics (specialty and practice setting), hyperkalaemia treatment objectives and strategies, rationale for management decisions and indicators of response and patient-reported perceptions of their hyperkalaemia treatment. Results: The enrolled cohort includes 1330 participants, mean age 68 years, of whom 31% were women. At baseline, 6% reported heart failure, 55% chronic kidney disease, 29% both and 9% neither. Most participants (57%) were taking an angiotensin-converting enzyme inhibitor, angiotensin receptor blocker or angiotensin receptor/neprilysin inhibitor at baseline. Mineralocorticoid receptor antagonist use was lower (14%). Conclusions: The prospective TRACK study will shed light on practitioners' hyperkalaemia management decision-making and assess the impact of their decisions on hyperkalaemia recurrence. Understanding practitioners' underlying thought processes will facilitate efforts to improve hyperkalaemia management.ClinicalTrials.gov: NCT05408039.

Indexed as

chronic kidney diseaseheart failurehyperkalaemia managementRAASireal-world evidence

Identifiers

PMID39464260
PMCPMC11503019

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.