Evidence map›Paper›PMID 39464161›Full record

ArticlebioRxiv : the preprint server for biology2024

Glucose-dependent glycosphingolipid biosynthesis fuels CD8

Joseph Longo, Lisa M DeCamp, Brandon M Oswald, Robert Teis, Alfredo Reyes-Oliveras, Michael S Dahabieh, Abigail E Ellis, Michael P Vincent, Hannah Damico, Kristin L Gallik and 11 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

21 authors.

Joseph LongoDepartment of Metabolism and Nutritional Programming, Van Andel Institute, Grand Rapids, MI, USA.ORCID 0000-0002-9580-5105
Lisa M DeCampDepartment of Metabolism and Nutritional Programming, Van Andel Institute, Grand Rapids, MI, USA.
Brandon M OswaldDepartment of Metabolism and Nutritional Programming, Van Andel Institute, Grand Rapids, MI, USA.
Robert TeisDepartment of Metabolism and Nutritional Programming, Van Andel Institute, Grand Rapids, MI, USA.
Alfredo Reyes-OliverasDepartment of Cell Biology, Van Andel Institute, Grand Rapids, MI, USA.
Michael S DahabiehDepartment of Metabolism and Nutritional Programming, Van Andel Institute, Grand Rapids, MI, USA.
Abigail E EllisMass Spectrometry Core, Van Andel Institute, Grand Rapids, MI, USA.
Michael P VincentMass Spectrometry Core, Van Andel Institute, Grand Rapids, MI, USA.
Hannah DamicoBioinformatics and Biostatistics Core, Van Andel Institute, Grand Rapids, MI, USA.
Kristin L GallikOptical Imaging Core, Van Andel Institute, Grand Rapids, MI, USA.
Shelby E ComptonDepartment of Metabolism and Nutritional Programming, Van Andel Institute, Grand Rapids, MI, USA.
Colt D CapanMass Spectrometry Core, Van Andel Institute, Grand Rapids, MI, USA.
Kelsey S WilliamsDepartment of Metabolism and Nutritional Programming, Van Andel Institute, Grand Rapids, MI, USA.
Corinne R EsquibelOptical Imaging Core, Van Andel Institute, Grand Rapids, MI, USA.
Zachary B MadajBioinformatics and Biostatistics Core, Van Andel Institute, Grand Rapids, MI, USA.
Hyoungjoo LeeMass Spectrometry Core, Van Andel Institute, Grand Rapids, MI, USA.
Dominic G RoyCentre de Recherche du Centre Hospitalier de l'Université de Montréal, Montréal, Canada.
Connie M KrawczykDepartment of Metabolism and Nutritional Programming, Van Andel Institute, Grand Rapids, MI, USA.
Brian B HaabDepartment of Cell Biology, Van Andel Institute, Grand Rapids, MI, USA.
Ryan D SheldonMass Spectrometry Core, Van Andel Institute, Grand Rapids, MI, USA.
Russell G JonesDepartment of Metabolism and Nutritional Programming, Van Andel Institute, Grand Rapids, MI, USA.

Funding

Ketone Body Metabolism in CD8+ T Cell ResponsesR01AI165722 · NIAID · VAN ANDEL RESEARCH INSTITUTE · PI JONES, RUSSELL GRAHAM · 2022 to 2025
$3.3M
Chromatin architecture as a determinant of dendritic cell functionR21AI153997 · NIAID · VAN ANDEL RESEARCH INSTITUTE · PI KRAWCZYK, CONNIE · 2020 to 2021
$523k
NIAID NIH HHS R01 AI165722NIAID NIH HHS R21 AI153997
6 · The paper itself

Abstract

Glucose is essential for T cell proliferation and function, yet its specific metabolic roles

Indexed as

CD8+ T cellscytotoxic functionglucoseglycosphingolipidsimmunometabolismlipidomicslipid raftsmetabolomicsnucleotide sugar metabolismUGCG

Identifiers

PMID39464161
PMCPMC11507764

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.