Evidence map›Paper›PMID 39464158›Full record

ArticlebioRxiv : the preprint server for biology2025

The regulatory architecture of gene expression variation in

Avery Davis Bell, Francisco Valencia, Annalise B Paaby

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Avery Davis BellSchool of Biological Sciences, Georgia Institute of Technology, 950 Atlantic Drive NW, Atlanta, GA 30332-2000, USA.ORCID 0000-0002-1837-302X
Francisco ValenciaSchool of Biological Sciences, Georgia Institute of Technology, 950 Atlantic Drive NW, Atlanta, GA 30332-2000, USA.
Annalise B PaabySchool of Biological Sciences, Georgia Institute of Technology, 950 Atlantic Drive NW, Atlanta, GA 30332-2000, USA.ORCID 0000-0003-1422-047X

Funding

Genetic Architecture and Developmental Consequences of Conditionally Functional MutationsR35GM119744 · NIGMS · GEORGIA INSTITUTE OF TECHNOLOGY · PI PAABY, ANNALISE BLOSS · 2016 to 2020
$1.8M
NIGMS NIH HHS R35 GM119744
6 · The paper itself

Abstract

An outstanding question in the evolution of gene expression is the composition of the underlying regulatory architecture and the processes that shape it. Mutations affecting a gene's expression may reside locally in

Indexed as

Allele-specific expressionC. elegansGene expressionNatural genetic variationRegulatory architectureRegulatory evolutionRNA sequencing

Identifiers

PMID39464158
PMCPMC11507773

What OpenQuestion holds

Textmetadata
LicenceCC BY-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.