Evidence map›Paper›PMID 39464055›Full record

ArticlebioRxiv : the preprint server for biology2024

A thermodynamic bottleneck in the TCA cycle contributes to acetate overflow in

Nabia Shahreen, Jongsam Ahn, Adil Alsiyabi, Niaz B Chowdhury, Dhananjay Shinde, Sujata S Chaudhari, Kenneth W Bayles, Vinai Chittezham Thomas, Rajib Saha

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Nabia ShahreenUniversity of Nebraska-Lincoln.
Jongsam AhnUniversity of Nebraska Medical Center.
Adil AlsiyabiUniversity of Nizwa.
Niaz B ChowdhuryUniversity of Nebraska-Lincoln.
Dhananjay ShindeUniversity of Nebraska Medical Center.
Sujata S ChaudhariUniversity of Nebraska Medical Centre.
Kenneth W BaylesUniversity of Nebraska Medical Center.
Vinai Chittezham ThomasUniversity of Nebraska Medical Center.
Rajib SahaUniversity of Nebraska-Lincoln.ORCID 0000-0002-2974-0243

Funding

The S. aureus biofilm lifecycleP01AI083211 · NIAID · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI KIELIAN, TAMMY L · 2009 to 2023
$32.1M
The role of arginine catabolic pathways in modulating staphylococcal fitnessR01AI125588 · NIAID · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI THOMAS, VINAI · 2018 to 2022
$1.9M
A Predictive Modeling Framework to Dissect the Dynamic Immunometabolic Responses to Pathogenic infection and the Kinetic Reprogramming of Metabolism in Cancer Cell SystemR35GM143009 · NIGMS · UNIVERSITY OF NEBRASKA LINCOLN · PI SAHA, RAJIB · 2021 to 2025
$1.8M
NIAID NIH HHS P01 AI083211NIAID NIH HHS R01 AI125588NIGMS NIH HHS R35 GM143009
6 · The paper itself

Abstract

During aerobic growth,

Indexed as

Membrane crowdingRedox imbalanceThermodynamic bottleneck

Identifiers

PMID39464055
PMCPMC11507952

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.