Evidence map›Paper›PMID 39463997›Full record

ArticlebioRxiv : the preprint server for biology2024

Molecular and cell phenotype programs in oral epithelial cells directed by co-exposure to arsenic and smokeless tobacco.

Samrat Das, Shefali Thakur, Vincent Cahais, François Virard, Liesel Claeys, Claire Renard, Cyrille Cuenin, Marie-Pierre Cros, Stéphane Keïta, Assunta Venuti and 5 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors.

Samrat DasEpigenomics and Mechanisms Branch, International Agency for Research on Cancer, Lyon, France.ORCID 0000-0002-7672-3374
Shefali ThakurEpigenomics and Mechanisms Branch, International Agency for Research on Cancer, Lyon, France.ORCID 0000-0002-8252-8671
Vincent CahaisEpigenomics and Mechanisms Branch, International Agency for Research on Cancer, Lyon, France.ORCID 0000-0001-5530-4368
François VirardEpigenomics and Mechanisms Branch, International Agency for Research on Cancer, Lyon, France.ORCID 0000-0001-7570-1088
Liesel ClaeysEpigenomics and Mechanisms Branch, International Agency for Research on Cancer, Lyon, France.ORCID 0000-0001-9566-1861
Claire RenardEpigenomics and Mechanisms Branch, International Agency for Research on Cancer, Lyon, France.ORCID 0000-0001-6523-3962
Cyrille CueninEpigenomics and Mechanisms Branch, International Agency for Research on Cancer, Lyon, France.
Marie-Pierre CrosEpigenomics and Mechanisms Branch, International Agency for Research on Cancer, Lyon, France.
Stéphane KeïtaEpigenomics and Mechanisms Branch, International Agency for Research on Cancer, Lyon, France.
Assunta VenutiEpigenomics and Mechanisms Branch, International Agency for Research on Cancer, Lyon, France.ORCID 0000-0001-5438-1724
Cécilia SirandEpigenomics and Mechanisms Branch, International Agency for Research on Cancer, Lyon, France.
Akram GhantousEpigenomics and Mechanisms Branch, International Agency for Research on Cancer, Lyon, France.ORCID 0000-0002-2582-6402
Zdenko HercegEpigenomics and Mechanisms Branch, International Agency for Research on Cancer, Lyon, France.ORCID 0000-0003-4109-3154
Michael KorenjakEpigenomics and Mechanisms Branch, International Agency for Research on Cancer, Lyon, France.ORCID 0000-0003-3242-7968
Jiri ZavadilEpigenomics and Mechanisms Branch, International Agency for Research on Cancer, Lyon, France.ORCID 0000-0003-0640-5562

Funding

Modeling mutational landscapes of primary cancers using an in vitro cell immortalization assayR03ES025023 · NIEHS · INTERNATIONAL AGENCY FOR RES ON CANCER · PI OLIVIER, MAGALI · 2015 to 2016
$113k
NIEHS NIH HHS R03 ES025023
6 · The paper itself

Abstract

Chronic arsenic exposure can lead to various health issues, including cancer. Concerns have been mounting about the enhancement of arsenic toxicity through co-exposure to various prevalent lifestyle habits. Smokeless tobacco products are commonly consumed in South Asian countries, where their use frequently co-occurs with exposure to arsenic from contaminated groundwater. To decipher the

Indexed as

apoptosisarsenicDNA methylationgene expressioninflammatory responselive cell analysisoral cellssmokeless tobaccowhole-exome sequencing

Identifiers

PMID39463997
PMCPMC11507705

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.