Evidence map›Paper›PMID 39463962›Full record

ArticlebioRxiv : the preprint server for biology2024

Shh signaling directs dorsal ventral patterning in the regenerating

Avery Angell Swearer, Samuel Perkowski, Andrea Wills

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Avery Angell SwearerDepartment of Biochemistry, University of Washington School of Medicine.ORCID 0000-0002-0258-4869
Samuel PerkowskiDepartment of Biochemistry, University of Washington School of Medicine.
Andrea WillsDepartment of Biochemistry, University of Washington School of Medicine.ORCID 0000-0003-3647-8105

Funding

Training in Cellular & Molecular BiologyT32GM136534 · NIGMS · UNIVERSITY OF WASHINGTON · PI Andrew Atwell Oberst, LARRY S ZWEIFEL · 2021 to 2026
$5.8M
Transcriptional regulatory mechanisms of vertebrate regenerationR01NS099124 · NINDS · UNIVERSITY OF WASHINGTON · PI Andrea Elizabeth Wills · 2017 to 2026
$3.3M
NIGMS NIH HHS T32 GM136534NINDS NIH HHS R01 NS099124
6 · The paper itself

Abstract

Tissue development and regeneration rely on the deployment of embryonic signals to drive progenitor activity and thus generate complex cell diversity and organization. One such signal is Sonic Hedgehog (Shh), which establishes the dorsal-ventral (D/V) axis of the spinal cord during embryogenesis. However, the existence of this D/V axis and its dependence on Shh signaling during regeneration varies by species. Here we investigate the function of Shh signaling in patterning the D/V axis during spinal cord regeneration in

Identifiers

PMID39463962
PMCPMC11507847

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.