Evidence map›Paper›PMID 39463779›Full record

ArticleCase reports in gastrointestinal medicine2024

White Globe Appearance-Like Findings Indicating Intralymphatic Cancer Involvement Beneath the Epithelium in Gastric Cancer.

Hiroki Maruyama, Taku Yamagata, Yoshihide Kanno, Takeshi Shimizu, Takuho Itasaka, Fumiyoshi Fujishima, Takashi Sawai, Kei Ito

Abstract readCase Reports
In one paragraph

Article in Case reports in gastrointestinal medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hiroki MaruyamaDepartment of Gastroenterology, Sendai City Medical Center, Miyagi, Japan.ORCID https://orcid.org/0009-0008-7845-2281
Taku YamagataDepartment of Gastroenterology, Sendai City Medical Center, Miyagi, Japan.ORCID https://orcid.org/0000-0001-8624-7669
Yoshihide KannoDepartment of Gastroenterology, Sendai City Medical Center, Miyagi, Japan.ORCID https://orcid.org/0000-0002-2044-5483
Takeshi ShimizuDepartment of Gastroenterology, Sendai City Medical Center, Miyagi, Japan.ORCID https://orcid.org/0000-0003-2908-6007
Takuho ItasakaDepartment of Gastroenterology, Sendai City Medical Center, Miyagi, Japan.ORCID https://orcid.org/0009-0005-2736-2786
Fumiyoshi FujishimaDepartment of Pathology, Tohoku University Hospital, Miyagi, Japan.ORCID https://orcid.org/0000-0001-8400-5551
Takashi SawaiDepartment of Pathology, Sendai City Medical Center, Miyagi, Japan.ORCID https://orcid.org/0000-0001-5983-6214
Kei ItoDepartment of Gastroenterology, Sendai City Medical Center, Miyagi, Japan.ORCID https://orcid.org/0000-0002-0023-7919

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 75-year-old female was diagnosed with a type 0-I, moderately differentiated, early gastric carcinoma on the posterior wall of the middle gastric body during esophagogastroduodenoscopy (EGD). Several small whitish structures, referred to as white globe appearances (WGAs), were noted on the oral side outside the demarcation line of the cancerous protrusion. Although this area was flat without cancerous mucosal changes on the surface, subepithelial cancer extension was suspected. The histopathology of the resected specimen revealed that the carcinoma with submucosal invasion had significant lymphatic invasion with submucosal lateral extent along lymphatic vessels. In some areas, the carcinoma within the lymphatic vessels regressed from the submucosal layer towards the mucosal lamina propria, penetrating the muscularis mucosas. The intralymphatic carcinoma reaching just beneath the epithelium was considered to manifest WGA features during endoscopy.

Indexed as

early gastric cancerlateral spreadlymphatic invasionmagnifying endoscopynarrow-band imaging

Identifiers

PMID39463779
PMCPMC11512643

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.