Evidence map›Paper›PMID 39463545›Full record

ArticleCureus2024

A Unique Presentation of Diffuse Intraductal Papillary Mucinous Neoplasm of Bile Duct Successfully Treated With Orthotopic Liver Transplant and Pancreaticoduodenectomy Procedure: A Case Report.

Yichen Fang, Catherine O'Leary, Hannah Lowe, Danielle H Carpenter, Henry B Randall, Mustafa D Nazzal

Abstract readCase Reports
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yichen FangDepartment of Surgery, Saint Louis University School of Medicine, Saint Louis, USA.
Catherine O'LearyDepartment of Medicine, Saint Louis University School of Medicine, Saint Louis, USA.
Hannah LoweDepartment of Surgery, Saint Louis University Hospital, Saint Louis, USA.
Danielle H CarpenterDepartment of Pathology, Saint Louis University Hospital, Saint Louis, USA.
Henry B RandallDepartment of Surgery, Saint Louis University Hospital, Saint Louis, USA.
Mustafa D NazzalDepartment of Surgery, Saint Louis University Hospital, Saint Louis, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biliary intraepithelial neoplasm (BilIN) and intraductal papillary mucinous neoplasm of the bile duct (IPMN-B) are recognized as the two main precursors to biliary carcinoma. Surgical resection is the mainstay of treatment, with pancreaticoduodenectomy for extrahepatic biliary duct disease involving the pancreatic or distal portion of the bile duct, and bile duct and liver resection for perihilar and intrahepatic bile duct involvement. For diffuse IPMN-B with involvement of the entirety of the biliary epithelium of both intrahepatic and extrahepatic biliary systems, there is no well-documented consensus on treatment due to its rarity. Therefore, we present a case of a 56-year-old male with diffuse IPMN-B managed with combined orthotopic liver transplant and pancreaticoduodenectomy. As such, the clinical presentation, diagnostics, and unique course of intervention for our patient are described. This case provides insight into the topic of managing IPMN-Bs, particularly with diffuse biliary tree involvement. With such a rare disease with wildly varied presentations, consensus on a set treatment algorithm is nearly impossible to establish. This case describes one treatment pathway we found to be successful.

Indexed as

bile ductcholangiocarcinomadysplasiaintraductal papillary mucinous neoplasm of the bile duct (ipmn-b)orthotopic liver transplant (olt)pancreaticoduodenectomy

Identifiers

PMID39463545
PMCPMC11506687

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.