Evidence map›Paper›PMID 39463408›Full record

ArticleScientific reports2024

Preparation and tissue structure analysis of horse bone collagen peptide.

Jindi Wu, Heya Na, Fan Bai, Siyu Li, Hao Gao, Rina Sha

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jindi WuCollege of Food Science and Engineering, Inner Mongolia Agricultural University, Hohhot, 010018, China.
Heya NaCollege of Food Science and Engineering, Inner Mongolia Agricultural University, Hohhot, 010018, China.
Fan BaiVeterinary Research Institute, Inner Mongolia Academy of Agricultural and Animal Husbandry Sciences, Hohhot, 010031, China.
Siyu LiCollege of Food Science and Engineering, Inner Mongolia Agricultural University, Hohhot, 010018, China.
Hao GaoCollege of Food Science and Engineering, Inner Mongolia Agricultural University, Hohhot, 010018, China.
Rina ShaCollege of Food Science and Engineering, Inner Mongolia Agricultural University, Hohhot, 010018, China. spsharina@imau.edu.cn.

Funding

Natural Science Foundation of Inner Mongolia Autonomous Region 2022QN03026Postgraduate Training fund RC1900004555
6 · The paper itself

Abstract

Horse bone is rich in collagen, with a composition similar to that of human collagen. Collagen peptides supply nutrients needed for human growth that act as antioxidants, lower blood pressure. This study explored the extraction of collagen and the preparation of collagen short peptides from Mongolian horse bones. Bones were collected from horses of varying ages, and the collagen content along with calcium salt distribution were observed through staining and imaging analyses. Next, the bones were processed into a powder and then subjected to ultra-high-pressure processing for degreasing. The degreasing conditions were optimised by single-factor and orthogonal tests. Following this, collagen was extracted using an acid-enzymatic method, and its structural characteristics and thermal stability were assessed. The collagen short peptides were extracted from the collagen samples, and the effects of the enzymatic hydrolysis time, temperature, pH, and enzyme amount on the extraction rate were evaluated. Finally, the resulting collagen peptides were analysed for antioxidant activity. In summary, this experiment optimised the extraction conditions for horse bone collagen, demonstrating that the ultra-high-pressure method minimally affects collagen structure, and the extraction rate was high. Hence our method has significant development potential.

Indexed as

Bone and BonesCollagenPeptidesAnimalsAntioxidantsHorsesHydrogen-Ion ConcentrationHydrolysisTemperatureAntioxidantsCollagenPeptidesAntioxidant activityCollagen peptideHard tissue sectionMongolian horse bonesUltra-high pressure

Identifiers

PMID39463408
PMCPMC11514178

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.