Trial reportClinical oral investigations2024
Ex-vivo evaluation of clinically-set hydraulic sealers used with different canal dryness protocols and obturation techniques: a randomized clinical trial.
Trial report in Clinical oral investigations, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05808062 (The Effect of Different Canal Dryness Protocols on the Quality of Matched Single Cone Obturation), which is not on this map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effect of Different Canal Dryness Protocols on the Quality of Matched Single Cone Obturation: A Randomized Clinical Trial
Who cites it
5 citing papers in PubMed.
- Influence of apical root resection level and filling technique on the fracture resistance of endodontically treated teeth: a biomechanical study.Odontology · 2026Article
- Cytocompatibility, osteogenic potential, antibacterial and antibiofilm efficacy of a calcium-silicate-based intracanal medication.Odontology · 2026Article
- Physical properties comparison of four bioceramic vs. epoxy resin-based root canal sealers: an in vitro study.BMC oral health · 2026Article
- Physico-chemical analysis of eight pre-mixed hydraulic silicate sealers.Frontiers in dental medicine · 2026Article
- Apical delta filling with calcium silicate and epoxy resin sealers using different obturation techniques by microcomputed tomography.Journal of applied oral science : revista FOB · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThis 2-part randomized parallel triple-blind clinical trial adopts a unique model assessing clinically-set hydraulic calcium silicate-based sealers (HCSBS) after different root canal dryness protocols and obturation techniques.
methodsFor the first phase of the study, 24 teeth scheduled for orthodontic extractions were allocated into four groups according to the canal dryness protocol and the obturation technique. G1 (CLC-AHP): cold lateral compaction (CLC) with AH Plus sealer, G2 (CLC-ES-SD): CLC with Endosequence (ES) after standard canal(s) dryness (SD); G3 (SC-ES-SD): matching single-cone (SC) with ES after SD; G4 (SC-ES-PD): as G3 but after partial canal(s) dryness (PD). Teeth were extracted after one month of clinical service and examined for intracanal voids by micro-CT (2D & 3D). For the 2nd phase, another 24 teeth were allocated into four groups according to the root canal dryness protocol and the HCSBS used (ES or CeraSeal (CeS)). Teeth were extracted after one month and sectioned vertically for energy dispersive X-ray (EDX)/scanning electron microscope (SEM) examination. One-way ANOVA with Games-Howell post-hoc test and Chi-square test with multiple z-tests were used for statistical analysis.
resultsSC-PD showed the highest percentage of voids (p < 0.05). MicroCT scans as well as EDX/SEM examination showed that PD resulted in significantly larger interfacial gaps (p < 0.001) with more hydration products at the sealer/dentin interface than SD.
conclusionsBoth tested dryness protocols allowed the hydration of HCSBS and the formation of hydration products, thus standard dryness is recommended to reduce the incidence of intracanal voids. CLINICAL RELEVANCE: When using the single-cone obturation technique, intentional root canal moisture negatively affects the performance of HCSBS. PROTOCOL REGISTRATION: http://www. CLINICALTRIALS: gov, ID: NCT05808062.
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