Evidence map›Paper›PMID 39462721›Full record

ArticleHPB : the official journal of the International Hepato Pancreato Biliary Association2025

Robotic versus open pancreaticoduodenectomy in octogenarians: a comparative propensity score analysis of perioperative outcomes.

Andres A Abreu, Amr I Al Abbas, Jennie Meier, Ricardo E Nunez-Rocha, Emile Farah, Cecilia G Ethun, Matthew R Porembka, John C Mansour, Adam C Yopp, Herbert J Zeh Iii and 2 more

Abstract readComparative Study
In one paragraph

Article in HPB : the official journal of the International Hepato Pancreato Biliary Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Andres A AbreuUniversity of Texas Southwestern, Department of Surgery, Dallas, TX, USA.
Amr I Al AbbasUniversity of Texas Southwestern, Department of Surgery, Dallas, TX, USA.
Jennie MeierUniversity of Texas Southwestern, Department of Surgery, Dallas, TX, USA.
Ricardo E Nunez-RochaUniversity of Texas Southwestern, Department of Surgery, Dallas, TX, USA.
Emile FarahUniversity of Texas Southwestern, Department of Surgery, Dallas, TX, USA.
Cecilia G EthunUniversity of Texas Southwestern, Department of Surgery, Dallas, TX, USA.
Matthew R PorembkaUniversity of Texas Southwestern, Department of Surgery, Dallas, TX, USA.
John C MansourUniversity of Texas Southwestern, Department of Surgery, Dallas, TX, USA.
Adam C YoppUniversity of Texas Southwestern, Department of Surgery, Dallas, TX, USA.
Herbert J Zeh IiiUniversity of Texas Southwestern, Department of Surgery, Dallas, TX, USA.
Sam C WangUniversity of Texas Southwestern, Department of Surgery, Dallas, TX, USA.
Patricio M PolancoUniversity of Texas Southwestern, Department of Surgery, Dallas, TX, USA. Electronic address: patricio.polanco@utsouthwestern.edu.

Funding

UT Southwestern Medical Center Simmons Comprehensive Cancer CenterP30CA142543 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI MELANIE H. COBB · 2010 to 2026
$53.7M
NCI NIH HHS P30 CA142543
6 · The paper itself

Abstract

backgroundCompared to open pancreaticoduodenectomies (OPD), the robotic (RPD) approach decreases the rate of complication and the length of stay (LOS). However, it remains unknown if these benefits persist in octogenarians, who are at higher risk for perioperative morbidity and mortality.

methodsA retrospective analysis of the ACS-NSQIP database was performed to identify patients aged 80 years or older who underwent PD for pancreatic adenocarcinoma between 2015-2021. Patients who underwent RPD or OPD were compared using inversed probability weighting of the propensity score. Outcomes assessed include operative time, LOS, non-home discharge, major complications, unplanned readmission, return to the operating room, mortality, and clinically relevant postoperative pancreatic fistula.

resultsOf 30,751 patients, 1720 were octogenarians. One thousand six hundred twenty-five patients (94 %) underwent OPD, and 95 (6 %) underwent RPD. RPD was significantly associated with a reduced incidence of major complications (32.6 % vs. 45.6 %; p < 0.01) and a lower rate of non-home discharge (24.7 % vs. 34.3%; p < 0.05). However, RPD was associated with a longer operative time (438 min vs. 342 min; p < 0.0001). There was no difference in other assessed outcomes.

conclusionRPD may reduce major postoperative complications and non-home discharges compared to the open approach for octogenarians.

Indexed as

Pancreatic NeoplasmsPancreaticoduodenectomyPostoperative ComplicationsPropensity ScoreRobotic Surgical ProceduresAdenocarcinomaAged, 80 and overAge FactorsDatabases, FactualFemaleHumansLength of StayMaleOperative TimeRetrospective StudiesRisk Assessment

Identifiers

PMID39462721
PMCPMC12173463

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.