Evidence map›Paper›PMID 39462483›Full record

ArticleJournal of biophotonics2025

Deep Learning With Optical Coherence Tomography for Melanoma Identification and Risk Prediction.

Pei-Yu Lai, Tai-Yu Shih, Yu-Huan Chang, Chung-Hsing Chang, Wen-Chuan Kuo

Abstract read
In one paragraph

Article in Journal of biophotonics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Pei-Yu LaiInstitute of Biophotonics, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Tai-Yu ShihInstitute of Biophotonics, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Yu-Huan ChangInstitute of Biophotonics, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Chung-Hsing ChangHualien Tzu chi Hospital, Buddhist Tzu Chi Medical Foundation, Skin Institute, Hualien, Taiwan.
Wen-Chuan KuoInstitute of Biophotonics, National Yang Ming Chiao Tung University, Taipei, Taiwan.ORCID 0000-0001-7432-1948

Funding

National Health Research InstitutesNational Health Research Institutes, TaiwanNational Science and Technology CouncilNational Science and Technology Council, Taiwan MOST111-2112-M-A49-026National Science and Technology Council, Taiwan NHRI-EX113-11326EI
6 · The paper itself

Abstract

Malignant melanoma is the most severe skin cancer with a rising incidence rate. Several noninvasive image techniques and computer-aided diagnosis systems have been developed to help find melanoma in its early stages. However, most previous research utilized dermoscopic images to build a diagnosis model, and only a few used prospective datasets. This study develops and evaluates a convolutional neural network (CNN) for melanoma identification and risk prediction using optical coherence tomography (OCT) imaging of mice skin. Longitudinal tests are performed on four animal models: melanoma mice, dysplastic nevus mice, and their respective controls. The CNN classifies melanoma and healthy tissues with high sensitivity (0.99) and specificity (0.98) and also assigns a risk score to each image based on the probability of melanoma presence, which may facilitate early diagnosis and management of melanoma in clinical settings.

Indexed as

Deep LearningMelanomaTomography, Optical CoherenceAnimalsImage Processing, Computer-AssistedMiceRisk AssessmentSkin Neoplasmsconvolutional neural networkmelanomamice modeloptical coherence tomographyrisk prediction

Identifiers

PMID39462483
PMCPMC11700698

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.